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Proteintech

GSNOR, ADH5 Polyclonal Antibody, CoraLite® Plus 488

View all (21) ADH5 antibodies

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Product Details

CL488-11051

Applications
Tested Dilution
Publications

Flow Cytometry (Flow)

0.40 µg/10^6 cells in a 100 µL suspension
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

GSNOR,ADH5 fusion protein Ag1533

Conjugate

CoraLite® Plus 488 CoraLite® Plus 488 CoraLite® Plus 488

Excitation/Emission Max

493/522 nm

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.5% BSA

Contains

0.05% ProClin 300

Storage conditions

-20°C, store in dark

Shipping conditions

Wet ice

Target Information

This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ADH-B2; ADH5; alcohol dehydrogenase (class III), chi polypeptide; Alcohol dehydrogenase 2; Alcohol dehydrogenase 5; Alcohol dehydrogenase B2; Alcohol dehydrogenase class chi chain; alcohol dehydrogenase class III; Alcohol dehydrogenase class-3; Alcohol dehydrogenase class-III; class III alcohol dehydrogenase, chi subunit; epididymis secretory sperm binding protein Li 60p; FALDH; FDH; formaldehyde dehydrogenase; Glutathione-dependent formaldehyde dehydrogenase; GSH-FDH; S-(hydroxymethyl)glutathione dehydrogenase; S-nitrosoglutathione reductase; unnamed protein product

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Gene Aliases: Adh-2; ADH-3; Adh-5; Adh2; Adh3; ADH5; ADHX; AMEDS; BMFS7; FALDH; FDH; GSH-FDH; GSNOR; HEL-S-60p

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UniProt ID: (Human) P11766, (Rat) P12711, (Mouse) P28474

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Entrez Gene ID: (Human) 128, (Rat) 100145871, (Mouse) 11532

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Function(s)
alcohol dehydrogenase (NAD) activity fatty acid binding zinc ion binding electron carrier activity oxidoreductase activity formaldehyde dehydrogenase activity identical protein binding metal ion binding S-(hydroxymethyl)glutathione dehydrogenase activity S-nitrosoglutathione reductase activity S-(hydroxymethyl)glutathione dehydrogenase NADP activity S-(hydroxymethyl)glutathione dehydrogenase NAD activity protein homodimerization activity C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity aldo-keto reductase (NADP) activity isocitrate dehydrogenase activity mevaldate reductase activity gluconate dehydrogenase activity steroid dehydrogenase activity epoxide dehydrogenase activity 5-exo-hydroxycamphor dehydrogenase activity 2-hydroxytetrahydrofuran dehydrogenase activity acetoin dehydrogenase activity phenylcoumaran benzylic ether reductase activity D-xylose:NADP reductase activity L-arabinose:NADP reductase activity D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor steroid dehydrogenase activity, acting on the CH-CH group of donors (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity 3-hydroxymenthone dehydrogenase activity very long-chain-3-hydroxyacyl-CoA dehydrogenase activity dihydrotestosterone 17-beta-dehydrogenase activity (R)-2-hydroxyisocaproate dehydrogenase activity L-arabinose 1-dehydrogenase (NADP+) activity L-xylulose reductase (NAD+) activity 3-ketoglucose-reductase activity (R)-2-hydroxyglutarate dehydrogenase activity D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity dehydrogenase oxidoreductase metabolite interconversion enzyme
Process(es)
retinoid metabolic process respiratory system process lipid metabolic process fatty acid omega-oxidation response to lipopolysaccharide small molecule metabolic process positive regulation of blood pressure formaldehyde catabolic process response to nitrosative stress response to redox state ethanol catabolic process ethanol oxidation aging peptidyl-cysteine S-nitrosylation oxidation-reduction process
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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