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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • GSS Antibodies

          Proteintech

          GSS Polyclonal Antibody

          12 References
          View all (22) GSS antibodies

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          Cite GSS Polyclonal Antibody

          • Antibody Testing Data (6)
          GSS Antibody in Immunocytochemistry (ICC/IF)
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          GSS Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 6

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          GSS Antibody (15712-1-AP) in ICC/IF

          Immunofluorescent analysis of ( -20°C Ethanol ) fixed MDCK cells using 15712-1-AP (GSS antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          GSS Antibody in Immunocytochemistry (ICC/IF)
          GSS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GSS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GSS Antibody in Western Blot (WB)
          GSS Antibody in Western Blot (WB)
          GSS Antibody in Western Blot (WB)
          GSS Polyclonal Antibody

          Product Details

          15712-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          View 12 publications 12 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:400
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          -
          Product Specifications

          Species Reactivity

          Dog, Hamster, Human, Mouse, Pig, Rat

          Published species

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          GSS Fusion Protein Ag8338 (125-474 aa encoded by BC007927)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.3 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: RSDYMFQRS ADGSPALKQI EINTISASFG GLASRTPAVH RHVLSVLSKT KEAGKILSNN PSKGLALGIA KAWELYGSPN ALVLLIAQEK ERNIFDQRAI ENELLARNIH VIRRTFEDIS EKGSLDQDRR LFVDGQEIAV VYFRDGYMPR QYSLQNWEAR LLLERSHAAK CPDIATQLAG TKKVQQELSR PGMLEMLLPG QPEAVARLRA TFAGLYSLDV GEEGDQAIAE ALAAPSRFVL KPQREGGGNN LYGEEMVQAL KQLKDSEERA SYILMEKIEP EPFENCLLRP GSPARVVQCI SELGIFGVYV RQEKTLVMNK HVGHLLRTKA IEHADGGVAA GVAVLDNPYP V (125-474 aa encoded by BC007927)

          Target Information

          Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Glutathione synthase; Glutathione synthetase; GSH S; GSH synthetase; GSH-S; GSHB; MGC14098; OTTHUMP00000030711

          View more View less

          Gene Aliases: AI314904; GS-A/GS-B; GSH-S; GSHS; GSS; HEL-S-64p; HEL-S-88n

          View more View less

          UniProt ID: (Human) P48637, (Rat) P46413, (Mouse) P51855

          View more View less

          Entrez Gene ID: (Human) 2937, (Pig) 100152660, (Dog) 442962, (Rat) 25458, (Mouse) 14854, (Chinese hamster) 100753200

          View more View less

          Function(s)
          magnesium ion binding glutathione synthase activity protein binding ATP binding glycine binding protein homodimerization activity glutathione binding peptide binding nucleotide binding ligase activity metal ion binding ligase metabolite interconversion enzyme
          Process(es)
          cellular amino acid metabolic process glutathione biosynthetic process response to oxidative stress nervous system development aging response to xenobiotic stimulus response to nutrient levels response to tumor necrosis factor response to amino acid response to cadmium ion
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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