Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:1,000 | View 6 publications 6 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:100-1:400 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:500 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
GSS Fusion Protein Ag8338 (125-474 aa encoded by BC007927) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.3 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: RSDYMFQRS ADGSPALKQI EINTISASFG GLASRTPAVH RHVLSVLSKT KEAGKILSNN PSKGLALGIA KAWELYGSPN ALVLLIAQEK ERNIFDQRAI ENELLARNIH VIRRTFEDIS EKGSLDQDRR LFVDGQEIAV VYFRDGYMPR QYSLQNWEAR LLLERSHAAK CPDIATQLAG TKKVQQELSR PGMLEMLLPG QPEAVARLRA TFAGLYSLDV GEEGDQAIAE ALAAPSRFVL KPQREGGGNN LYGEEMVQAL KQLKDSEERA SYILMEKIEP EPFENCLLRP GSPARVVQCI SELGIFGVYV RQEKTLVMNK HVGHLLRTKA IEHADGGVAA GVAVLDNPYP V (125-474 aa encoded by BC007927)
Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Glutathione synthase; Glutathione synthetase; GSH S; GSH synthetase; GSH-S; GSHB; MGC14098; OTTHUMP00000030711
Gene Aliases: AI314904; GS-A/GS-B; GSH-S; GSHS; GSS; HEL-S-64p; HEL-S-88n
UniProt ID: (Human) P48637, (Rat) P46413, (Mouse) P51855
Entrez Gene ID: (Human) 2937, (Rat) 25458, (Mouse) 14854
Molecular Function:
ligase
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