This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: NLYGEEMVQA LKQLKDSEER ASYILMEKIE PEPFENCLLR PGSPARVVQC ISELGIFGVY VRQEKTLVMN KHVGHLLRTK AI
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 91%.
Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Glutathione synthase; Glutathione synthetase; GSH S; GSH synthetase; GSH-S; GSHB; MGC14098; OTTHUMP00000030711
Gene Aliases: GSHS; GSS; HEL-S-64p; HEL-S-88n
UniProt ID: (Human) P48637
Entrez Gene ID: (Human) 2937
Molecular Function: ligase