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Proteintech
GSTA3 Polyclonal Antibody
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Product Details
16703-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GSTA3 Fusion Protein Ag10101 (1-222 aa encoded by BC020619)
Conjugate
Form
Liquid
Concentration
0.31 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAGKPKLHY FNGRGRMEPI RWLLAAAGVE FEEKFIGSAE DLGKLRNDGS LMFQQVPMVE IDGIKLVQTR AILNYIASKY NLYGKDIKER ALIDMYTEGM ADLNEMILLL PLCRPEEKDA KIALIKEKTK SRYFPAFEKV LQSHGQDYLV GNKLSRADIS LVELLYYVEE LDSSLISNFP LLKALKTRIS NLPTVKKFLQ PGSPRKPPAD AKALEEARKI FRF (1-222 aa encoded by BC020619)
Target Information
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: glutathione S-alkyltransferase A3; glutathione S-aralkyltransferase A3; glutathione S-aryltransferase A3; Glutathione S-transferase A3; Glutathione S-transferase A3-3; Glutathione S-transferase alpha-5; Glutathione S-transferase Ya3; Glutathione S-transferase Yc; Glutathione S-transferase Yc-2; glutathione S-transferase Yc2 subunit; GST A5-5; GST class-alpha member 3; GST Yc2; MGC22232; S-(hydroxyalkyl)glutathione lyase A3
Gene Aliases: Gst2-3; GSTA3; GSTA3-3; Gsta5; Gstyc; Gstyc2; GTA3; Yc2
UniProt ID: (Human) Q16772, (Mouse) P30115, (Rat) P46418
Entrez Gene ID: (Human) 2940, (Mouse) 14859, (Rat) 494500
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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