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Invitrogen
GSTA3 Polyclonal Antibody
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Product Details
PA5-100256
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human GSTA3(Accession Q16772), corresponding to amino acid residues R15-L65.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total GSTA3.
Target Information
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: glutathione S-alkyltransferase A3; glutathione S-aralkyltransferase A3; glutathione S-aryltransferase A3; Glutathione S-transferase A3; Glutathione S-transferase A3-3; Glutathione S-transferase alpha-5; Glutathione S-transferase Ya3; Glutathione S-transferase Yc; Glutathione S-transferase Yc-2; glutathione S-transferase Yc2 subunit; GST A5-5; GST class-alpha member 3; GST Yc2; MGC22232; S-(hydroxyalkyl)glutathione lyase A3
Gene Aliases: Gst2-3; GSTA3; GSTA3-3; Gsta5; Gstyc; Gstyc2; GTA3; Yc2
UniProt ID: (Human) Q16772, (Mouse) P30115, (Rat) P46418
Entrez Gene ID: (Human) 2940, (Mouse) 14859, (Rat) 494500
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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