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Proteintech
GTDC1 Polyclonal Antibody
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Product Details
16666-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GTDC1 Fusion Protein Ag10145 (1-292 aa encoded by BC061699)
Conjugate
Form
Liquid
Concentration
0.24 mg/mL
Amount
36 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSILIIEAF YGGSHKQLVD LLQEELGDCV VYTLPAKKWH WRARTSALYF SQTIPISEHY RTLFASSVLN LTELAALRPD LGKLKKILYF HENQLIYPVK KCQERDFQYG YNQILSCLVA DVVVFNSVFN MESFLTSMGK FMKLIPDHRP KDLESIIRPK CQVIYFPIRF PDVSRFMPKH KTTHLKKMLG LKGNGGAVLS MALPFQPEQR DSEDLLKNFN SECDTHCGLD TARQEYLGNS LRQESDLKKS TSSDNSSSHH GENKQNLTVD PCDILGGVDN QQRLLHIVWP HRW (1-292 aa encoded by BC061699)
Target Information
The GTDC1 (Glycosyltransferase-Like Domain Containing 1) gene encodes a protein that is hypothesized to function as a glycosyltransferase. This gene has been implicated in several crucial biological processes, particularly in the nervous system. The GTDC1 cDNA is 2954 base pairs in length, encoding a protein of 458 amino acids, and shows high expression in tissues such as the lung, spleen, testis, and peripheral blood leukocytes. Genetic studies have highlighted its potential role in developmental disorders, such as global developmental delay and delayed speech and language development, linked to microdeletions encompassing the GTDC1 gene. Disruption of GTDC1 expression has been shown to affect neural progenitor cells and neurons, indicating its significance in neural development. Additionally, the gene holds evolutionary conservation, sharing 75% and 37% identity with its mouse and fruit fly counterparts, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: glycosyltransferase-like 1; Glycosyltransferase-like domain-containing protein 1; glycosyltransferase-like protein; mannosyltransferase candidate; Mannosyltransferase-like protein Xa; Mat-Xa; QTMAN; tRNA-queuosine alpha-mannosyltransferase; unnamed protein product
Gene Aliases: E330008O22Rik; GTDC1; Hmat-Xa; mat-Xa; QTMAN
UniProt ID: (Human) Q4AE62, (Rat) Q53E76, (Mouse) Q8BW56
Entrez Gene ID: (Human) 79712, (Rat) 362129, (Mouse) 227835
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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