Recommended positive controls: U87-MG.
Predicted reactivity: Mouse (96%), Rat (95%), Rhesus Monkey (100%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box. [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: general transcription factor 3C 4; General transcription factor 3C polypeptide 4; general transcription factor IIIC, polypeptide 4, 90kDa; TF3C-delta; TFIIIC 90 kDa subunit; Transcription factor IIIC 90 kDa subunit; Transcription factor IIIC subunit delta
Gene Aliases: GTF3C4; KAT12; TF3C-delta; TFIII90; TFIIIC290; TFIIIC90; TFIIICDELTA
UniProt ID: (Human) Q9UKN8
Entrez Gene ID: (Human) 9329