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Invitrogen
GTPBP2 Polyclonal Antibody
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FIGURE: 1 / 1
GTPBP2 Antibody (PA5-75936) in WB
Western blot analysis of GTPBP2 in Lane 1: JURKAT whole cell lysate (56 µg), Lane 2: THP-1 whole cell lysate (42 µg), Lane 3: the Thymus whole cell lysate of rat (39 µg), Lane 4: the Testis tissue lysate of mouse (47 µg). Samples were incubated with GTPBP2 polyclonal antibody (Product # PA5-75936) at a dilution of 1:1,000.
Product Details
PA5-75936
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues in Human GTPBP2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
Small G proteins act as molecular switches for regulation of variety of cellular processes, such as nuclear transport, signal transduction, membrane trafficking and protein synthesis. GTPBP2 (GTP-binding protein 2) is a 602 amino acid G protein that is expressed in kidney, skeletal muscle, testis, brain and thymus, though it is not detected in liver. Expression of GTPBP2 is enhanced by ©-interferon stimulation in HeLa cells, THP-1 cells and thioglycollate-elicited mouse peritoneal macrophages. There are four isoforms of GTPBP2 that are expressed as a result of alternative splicing events. Since mutation of the gene encoding GTPBP1 does not lead to any phenotypic abnormalities, it is thought that there may be a genetic redundancy to make up for GTPBP1 lack-of-function. GTPBP2 shares 44% sequence similarity with GTPBP1 and also overlaps in expression pattern, suggesting that the GTPBP2 gene may compensate for GTPBP1 genetic abnormalities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GTP-binding protein 2; GTP-binding-like protein 2; GTPBP2
Gene Aliases: GTPBP2; nmf205
UniProt ID: (Human) Q9BX10, (Mouse) Q3UJK4
Entrez Gene ID: (Human) 54676, (Mouse) 56055, (Rat) 363195
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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