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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 276 and 492 of Human GTPBP3|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-31323 targets GTPBP3 in WB applications and shows reactivity with Human samples.
The PA5-31323 immunogen is recombinant fragment corresponding to a region within amino acids 276 and 492 of Human GTPBP3.
This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
GTPBG3; mitochondrial; mitochondrial GTP-binding protein 1; MSS1; MTGP1; THDF1; tRNA modification GTPase GTPBP3
COXPD23; GTPBG3; GTPBP3; MSS1; MTGP1; THDF1