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          • Primary Antibodies ›
          • GALC Antibodies

          Proteintech

          Galc Polyclonal Antibody, CoraLite® Plus 488

          View all (8) GALC antibodies

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          Cite Galc Polyclonal Antibody, CoraLite® Plus 488

          Additional Information:
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          • Antibody Testing Data (1)
          Galc Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          Galc Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          Galc Antibody (CL488-11991) in IHC (P)

          Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse brain tissue using CoraLite Plus 488 Galc antibody (CL488-11991) at dilution of 1:200. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Galc Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Galc Polyclonal Antibody, CoraLite® Plus 488

          Product Details

          CL488-11991

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Galc fusion protein Ag3914
          3D Epitope / Immunogen

          Conjugate

          CoraLite® Plus 488 CoraLite® Plus 488 CoraLite® Plus 488

          Excitation/Emission Max

          493/522 nm

          Form

          Liquid

          Concentration

          1000 µg/mL

          Amount

          100 µg

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 0.5% BSA, 50% glycerol

          Contains

          0.05% ProClin 300

          Storage conditions

          -20°C, store in dark

          Shipping conditions

          Wet ice

          Product Specific Information

          Sequence of this protein is as follows: YYLKTVGHLE KGGSYVALTD GLGNLTIIIE TMSHQHSMCI RPYLPYYNVS HQLATFTLKG SLREIQELQV WYTKLGTPQQ RLHFKQLDTL WLLDGSGSFT LELEEDEIFT LTTLTTGRKG SYPPPPSSKP FPTNYKDDFN VEYPLFSEAP NFADQTGVFE YYMNNEDREH RFTL

          Target Information

          This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: 3.2.1.46; beta-galactosidase; Galactocerebrosidase; Galactocerebroside beta-galactosidase; Galactosylceramidase; Galactosylceramide beta-galactosidase; galactosylceraminidase; GALCERase; testis tissue sperm-binding protein Li 88E; testis tissue sperm-binding protein Li 89A; unnamed protein product

          View more View less

          Gene Aliases: 2310068B06Rik; A930008M05Rik; AW212969; AW413532; Gacy; GALC; twi; twitcher

          View more View less

          UniProt ID: (Human) P54803, (Mouse) P54818

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          Entrez Gene ID: (Human) 2581, (Rat) 314360, (Mouse) 14420

          View more View less

          Function(s)
          galactosylceramidase activity hydrolase activity hydrolase activity, acting on glycosyl bonds galactosidase
          Process(es)
          lipid metabolic process sphingolipid metabolic process galactosylceramide catabolic process lipid catabolic process myelination glycosphingolipid catabolic process carbohydrate metabolic process
          It has to be done as per old AB suggested Products section.

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