Proteintech

Galectin-1 Polyclonal Antibody

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Galectin-1 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of ( -20°C Ethanol) fixed U2OS cells using 11858-1-AP (Galectin-1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

Galectin-1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using 11858-1-AP ( Galectin-1 antibody at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

Galectin-1 Antibody in Western Blot (WB) — Human liver tissue were subjected to SDS PAGE followed by western blot with 11858-1-AP (GAL1,LGALS1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Product Details

11858-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 9 publications 9 publications

Immunohistochemistry (IHC)

View 5 publications 5 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Galectin-1 Fusion Protein Ag2432 (1-135 aa encoded by BC020675)

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.37 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Product Specific Information

Immunogen sequence: MACGLVASN LNLKPGECLR VRGEVAPDAK SFVLNLGKDS NNLCLHFNPR FNAHGDANTI VCNSKDGGAW GTEQREAVFP FQPGSVAEVC ITFDQANLTV KLPDGYEFKF PNRLNLEAIN YMAADGDFKI KCVAFD (1-135 aa encoded by B C020675)

Target Information

Galectin-1 belongs to a large family of carbohydrate-binding proteins called lectins. Galectin-1can be either monomeric or homodimeric and is found in a wide variety of cells and tissue types. Galectin-1 can control cell growth, proliferation, induce apoptosis of activated T cells while it can also modulate cytokine secretion or inhibit pro-inflammatory cytokine production. Galectin-1 plays an important role in acute and chronic inflammation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

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Bioinformatics

Protein Aliases: 14 kDa laminin-binding protein; 14 kDa lectin; beta-galactoside binding protein; Beta-galactoside-binding lectin L-14-I; beta-galactoside-binding protein 14kDa; DKFZp686E23103; Gal-1; Galaptin; Galectin-1; Galectin1; H-Galectin-1; HBL; HLBP14; HPL; Lactose-binding lectin 1; Lectin galactoside-binding soluble 1; lectin, galactose binding, soluble 1; lectin, galactoside binding soluble 1; lectin, galactoside-binding, soluble, 1; pm12; Putative MAPK-activating protein PM12; RL 14.5; S-Lac lectin 1

Gene Aliases: AA410090; Gal-1; GAL1; Galbp; galectin-1; GBP; L-14.5; L14; Lect14; LGALS1

UniProt ID: (Human) P09382, (Mouse) P16045, (Rat) P11762

Entrez Gene ID: (Human) 3956, (Mouse) 16852, (Rat) 56646

Molecular Function: extracellular matrix protein