This Antibody was verified by KnockOut to ensure that the antibody binds to the antigen stated. View Details
PA5-34819 targets Galectin 3 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-34819 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 184 of Galectin3 (Uniprot ID#P17931).
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Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis . In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
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Protein Aliases: 35 kDa lectin; advanced glycation end-product receptor 3; Carbohydrate-binding protein 35; CBP 35; CBP35; epsilon BP; Gal-3; GAL3; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; Galectin-3; GALIG; IgE binding protein; IgE-binding protein; L-31; L31; Laminin-binding protein; lectin galactoside-binding soluble 3 protein; Lectin L-29; lectin, galactose binding, soluble 3; lectin, galactoside-binding, soluble, 3; LGALS2; MAC-2 antigen; MAC2
Gene Aliases: AGE-R3; CBP30; CBP35; gal-3; GAL3; GALBP; GALIG; L-34; L31; LGALS2; LGALS3; MAC2