Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; CBP-30; epsilon BP; Gal-3; Galactose-specific lectin 3; Galectin-3; Galectin3; IgE binding protein; IgE-binding protein; L-29; L-34 galactoside-binding lectin; Laminin-binding protein; lectin galactoside-binding soluble 3 protein; Lectin L-29; lectin, galactose binding, soluble 3; Mac-2 antigen
Gene Aliases: AGE-R3; CBP30; gal-3; gal3; GBP; L-34; Lgals3; Mac-2
UniProt ID: (Rat) P08699
Molecular Function: extracellular matrix protein