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Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; CBP-30; cytogaligin; Gal-3; Galactose-specific lectin 3; Galectin-3; Galectin3; IgE-binding protein; L-29; Laminin-binding protein; Lectin L-29; lectin, galactoside-binding, soluble, 3; Mac-2 antigen; mitogaligin
Gene Aliases: galig; LGALS3
UniProt ID: (Rabbit) P47845
Entrez Gene ID: (Rabbit) 100009187
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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