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Proteintech
Galectin 9 Polyclonal Antibody
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Product Details
17938-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Galectin 9 Fusion Protein Ag12209 (1-323 aa encoded by BC110340)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Amount
25.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAFSGSQAP YLSPAVPFSG TIQGGLQDGL QITVNGTVLS SSGTRFAVNF QTGFSGNDIA FHFNPRFEDG GYVVCNTRQN GSWGPEERKT HMPFQKGMPF DLCFLVQSSD FKVMVNGILF VQYFHRVPFH RVDTISVNGS VQLSYISFQP PGVWPANPAP ITQTVIHTVQ SAPGQMFSTP AIPPMMYPHP AYPMPFITTI LGGLYPSKSI LLSGTVLPSA QRFHINLCSG NHIAFHLNPR FDENAVVRNT QIDNSWGSEE RSLPRKMPFV RGQSFSVWIL CEAHCLKVAV DGQHLFEYYH RLRNLPTINR LEVGGDIQLT HVQT (1-323 aa encoded by BC110340)
Target Information
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H and RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Ecalectin; Gal-9; Gal9; Galectin-9; Galectin9; HOM HD 21; lectin, galactose binding, soluble 5; lectin, galactoside-binding, soluble, 9; Tumor antigen HOM-HD-21; unnamed protein product; urate transporter/channel protein
Gene Aliases: AA407335; AI194909; AI265545; gal-9; galectin-9; HUAT; LGALS35; Lgals5; LGALS9; LGALS9A
UniProt ID: (Human) O00182, (Mouse) O08573
Entrez Gene ID: (Human) 3965, (Mouse) 16859
immune system process
natural killer cell tolerance induction
negative regulation of T-helper 1 type immune response
chemotaxis
inflammatory response
female pregnancy
positive regulation of gene expression
negative regulation of gene expression
response to lipopolysaccharide
regulation of interleukin-4 production
regulation of interleukin-5 production
negative regulation of chemokine production
negative regulation of interferon-gamma production
negative regulation of tumor necrosis factor production
positive regulation of interferon-gamma production
positive regulation of interleukin-1 beta production
positive regulation of interleukin-10 production
positive regulation of interleukin-12 production
positive regulation of interleukin-13 production
positive regulation of interleukin-4 production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response
toll-like receptor 2 signaling pathway
toll-like receptor 4 signaling pathway
p38MAPK cascade
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of mast cell degranulation
negative regulation of natural killer cell mediated cytotoxicity
negative regulation of activated T cell proliferation
positive regulation of viral entry into host cell
positive regulation of NF-kappaB transcription factor activity
maternal process involved in female pregnancy
positive regulation of activated T cell autonomous cell death
ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
response to interleukin-1
cellular response to interferon-gamma
positive regulation of transforming growth factor beta production
positive regulation of monocyte chemotactic protein-1 production
mature conventional dendritic cell differentiation
cellular response to virus
regulation of p38MAPK cascade
positive regulation of NIK/NF-kappaB signaling
positive regulation of T cell migration
positive regulation of dendritic cell chemotaxis
negative regulation of CD4-positive, alpha-beta T cell proliferation
positive regulation of CD4-positive, alpha-beta T cell proliferation
positive regulation of dendritic cell apoptotic process
positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
positive regulation of dendritic cell differentiation
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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