Invitrogen

Galectin 9 Polyclonal Antibody

Advanced Verification

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details

View all (34) Galectin 9 antibodies

Questions & Answers

Questions & Answers

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Galectin 9 Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of Galectin 9 in human rectum and skeletal muscle tissues using Galectin 9 Polyclonal Antibody (Product # PA5-61469). Corresponding LGALS9 RNA-seq data are presented for the same tissues.

Galectin 9 Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of Galectin 9 in human lymph node using Galectin 9 Polyclonal Antibody (Product # PA5-61469) shows strong cytoplasmic positivity in non - germinal center cells.

Galectin 9 Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of Galectin 9 in human rectum using Galectin 9 Polyclonal Antibody (Product # PA5-61469) shows strong cytoplasmic positivity in glandular cells.

Galectin 9 Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of Galectin 9 in human colon using Galectin 9 Polyclonal Antibody (Product # PA5-61469) shows strong cytoplasmic positivity in glandular cells.

Galectin 9 Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of Galectin 9 in human skeletal muscle using Galectin 9 Polyclonal Antibody (Product # PA5-61469) shows no positivity in myocytes.

Galectin 9 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of Galectin 9 demonstrates antibody specificity. Immunohistochemical analysis of Galectin 9 using anti-Galectin 9 Polyclonal Antibody (Product # PA5-61469), shows significant staining of Galectin 9 in human rectum and shows minimal or weak staining in human skeletal muscle tissues. The relative expression levels of Galectin 9 within each tissue is shown using RNA-Seq. {RE}

Product Details

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Galectin 9

Conjugate

Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

RRID

AB_2641833

Product Specific Information

Immunogen sequence: RFDENAVVRN TQIDNSWGSE ERSLPRKMPF VRGQSFSVWI LCEAHCLKVA VDGQHLFEYY HRLRNLPTIN

Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 80%.

Target Information

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H and RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Ecalectin; Gal-9; Gal9; Galectin-9; Galectin9; HOM HD 21; lectin, galactoside binding soluble 9; lectin, galactoside-binding, soluble, 9; Tumor antigen HOM-HD-21; urate transporter/channel protein

Gene Aliases: HUAT; LGALS9; LGALS9A

UniProt ID: (Human) A7VJG6

Entrez Gene ID: (Human) 3965

Molecular Function: extracellular matrix protein

natural killer cell tolerance induction chemotaxis inflammatory response female pregnancy positive regulation of gene expression negative regulation of gene expression response to lipopolysaccharide regulation of interleukin-4 production regulation of interleukin-5 production negative regulation of chemokine production negative regulation of interferon-gamma production negative regulation of tumor necrosis factor production positive regulation of interleukin-4 production positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response toll-like receptor 2 signaling pathway toll-like receptor 4 signaling pathway p38MAPK cascade positive regulation of NF-kappaB import into nucleus positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of mast cell degranulation negative regulation of natural killer cell mediated cytotoxicity negative regulation of activated T cell proliferation positive regulation of viral entry into host cell positive regulation of interleukin-1 beta secretion positive regulation of NF-kappaB transcription factor activity maternal process involved in female pregnancy positive regulation of activated T cell autonomous cell death ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade response to interleukin-1 cellular response to interferon-gamma positive regulation of transforming growth factor beta production positive regulation of monocyte chemotactic protein-1 production mature conventional dendritic cell differentiation cellular response to virus regulation of p38MAPK cascade positive regulation of interferon-gamma secretion positive regulation of tumor necrosis factor secretion positive regulation of interleukin-8 secretion positive regulation of dendritic cell chemotaxis negative regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of interleukin-13 secretion positive regulation of dendritic cell apoptotic process positive regulation of interleukin-6 secretion positive regulation of interleukin-10 secretion positive regulation of interleukin-12 secretion positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell positive regulation of dendritic cell differentiation positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Process(es)

signal transducer activity galactose binding enzyme binding carbohydrate binding disaccharide binding