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Invitrogen
Galectin 9 Polyclonal Antibody
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FIGURE: 1 / 4
Galectin 9 Antibody (PA5-85496) in WB
Western blot was performed using Anti-Galectin 9 Polyclonal Antibody (Product # PA5-85496) and a ~36 kDa band corresponding to 36 kDa beta-galactoside-binding lectin was observed across cell lines tested. Whole cell extracts (15 µg lysate) of HUVEC (Lane 1), THP-1 (Lane 2), THP-1 treated with Rec. human TGF beta 1 (2 ng/mL for 24 hrs) (Lane 3), U-937 (Lane 4), MOLT-4 (Lane 5), PANC-1 (Lane 6), SH-SY5Y (Lane 7), Daudi (Lane 8) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0321BOX). Resolved proteins were then tr... View More
Product Details
PA5-85496
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Galectin 9. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Keep as concentrated solution.
Positive Control: LGALS9 transfected 293T lysates.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H and RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ecalectin; Gal-9; Gal9; Galectin-9; Galectin9; HOM HD 21; lectin, galactoside-binding, soluble, 9; Tumor antigen HOM-HD-21; unnamed protein product; urate transporter/channel protein
Gene Aliases: HUAT; LGALS9; LGALS9A
UniProt ID: (Human) O00182
Entrez Gene ID: (Human) 3965
immune system process
natural killer cell tolerance induction
negative regulation of T-helper 1 type immune response
chemotaxis
inflammatory response
female pregnancy
positive regulation of gene expression
negative regulation of gene expression
response to lipopolysaccharide
regulation of interleukin-4 production
regulation of interleukin-5 production
negative regulation of chemokine production
negative regulation of interferon-gamma production
negative regulation of tumor necrosis factor production
positive regulation of interferon-gamma production
positive regulation of interleukin-1 beta production
positive regulation of interleukin-10 production
positive regulation of interleukin-12 production
positive regulation of interleukin-13 production
positive regulation of interleukin-4 production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response
toll-like receptor 2 signaling pathway
toll-like receptor 4 signaling pathway
p38MAPK cascade
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of mast cell degranulation
negative regulation of natural killer cell mediated cytotoxicity
negative regulation of activated T cell proliferation
positive regulation of viral entry into host cell
positive regulation of NF-kappaB transcription factor activity
maternal process involved in female pregnancy
positive regulation of activated T cell autonomous cell death
ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
response to interleukin-1
cellular response to interferon-gamma
positive regulation of transforming growth factor beta production
positive regulation of monocyte chemotactic protein-1 production
mature conventional dendritic cell differentiation
cellular response to virus
regulation of p38MAPK cascade
positive regulation of NIK/NF-kappaB signaling
positive regulation of T cell migration
positive regulation of dendritic cell chemotaxis
negative regulation of CD4-positive, alpha-beta T cell proliferation
positive regulation of CD4-positive, alpha-beta T cell proliferation
positive regulation of dendritic cell apoptotic process
positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
positive regulation of dendritic cell differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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