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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Gelsolin Antibodies

          Proteintech

          Gelsolin Polyclonal Antibody

          11 References
          View all (32) Gelsolin antibodies

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          Cite Gelsolin Polyclonal Antibody

          • Antibody Testing Data (7)
          Gelsolin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          Gelsolin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 7

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          Gelsolin Antibody (11644-2-AP) in IHC (P)

          Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using 11644-2-AP ( Gelsolin Antibody) at dilution of 1:200 (under 40x lens). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Gelsolin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Gelsolin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Gelsolin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Gelsolin Antibody in Western Blot (WB)
          Gelsolin Antibody in Western Blot (WB)
          Gelsolin Antibody in Western Blot (WB)
          Gelsolin Antibody in Western Blot (WB)
          Gelsolin Polyclonal Antibody

          Product Details

          11644-2-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          View 6 publications 6 publications

          Immunohistochemistry (IHC)

          -
          View 3 publications 3 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunocytochemistry (ICC/IF)

          -
          View 2 publications 2 publications
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Gelsolin Fusion Protein Ag2239 (433-782 aa encoded by BC026033)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.13 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MAAQHGMDD DGTGQKQIWR IEGSNKVPVD PATYGQFYGG DSYIILYNYR HGGRQGQIIY NWQGAQSTQD EVAASAILTA QLDEELGGTP VQSRVVQGKE PAHLMSLFGG KPMIIYKGGT SREGGQTAPA STRLFQVRAN SAGATRAVEV LPKAGALNSN DAFVLKTPSA AYLWVGTGAS EAEKTGAQEL LRVLRAQPVQ VAEGSEPDGF WEALGGKAAY RTSPRLKDKK MDAHPPRLFA CSNKIGRFVI EEVPGELMQE DLATDDVMLL DTWDQVFVWV GKDSQEEEKT EALTSAKRYI ETDPANRDRR TPITVVKQGF EPPSFVGWFL GWDDDYWSVD PLDRAMAELA A (433-782 aa encoded by BC026033)

          Target Information

          The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Actin-depolymerizing factor; ADF; ADFBrevin; AGEL; Brevin; DKFZp313L0718; Gelsolin; RP11-477J21.1

          View more View less

          Gene Aliases: ADF; AGEL; Gsb; GSN

          View more View less

          UniProt ID: (Human) P06396, (Rat) Q68FP1, (Mouse) P13020

          View more View less

          Entrez Gene ID: (Human) 2934, (Rat) 296654, (Mouse) 227753

          View more View less

          Function(s)
          actin binding calcium ion binding protein binding protein domain specific binding myosin II binding metal ion binding non-motor actin binding protein
          Process(es)
          phagocytosis, engulfment aging positive regulation of gene expression oligodendrocyte development striated muscle atrophy extracellular matrix disassembly actin filament polymerization protein destabilization tissue regeneration sequestering of actin monomers cellular protein metabolic process actin nucleation response to ethanol negative regulation of viral entry into host cell phosphatidylinositol-mediated signaling actin filament severing barbed-end actin filament capping positive regulation of actin nucleation response to folic acid actin filament capping cilium morphogenesis cellular response to cadmium ion regulation of podosome assembly actin filament reorganization renal protein absorption hepatocyte apoptotic process positive regulation of keratinocyte apoptotic process regulation of wound healing, spreading of epidermal cells regulation of establishment of T cell polarity regulation of plasma membrane raft polarization regulation of receptor clustering positive regulation of protein processing in phagocytic vesicle amyloid fibril formation positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway apoptotic process actin polymerization or depolymerization vesicle-mediated transport regulation of cell adhesion wound healing cell projection organization
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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