For Western Blot, this antibody has non-specific bands at 120 kDa,140 kDa and 52 kDa.
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type . Multiple transcript variants encoding several different isoforms have been found for this gene.
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Protein Aliases: Actin-depolymerizing factor; ADF; AGEL; Brevin; Gelsolin; RP11-477J21.1, DKFZp313L0718, ADF
Gene Aliases: ADF; AGEL; Gsb; GSN