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Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human HepG2 whole cell, human THP-1 whole cell, human U251 whole cell, monkey COS-7 whole cell, rat C6 whole cell, mouse NIH/3T3 whole cell. IHC: Human Lung Cancer tissue, Human Intestinal Cancer tissue, Rat Cardiac Muscle tissue. ICC/IF: U20S cell, NIH3T3 Cell. Flow: U87 cell.
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Actin-depolymerizing factor; ADF; ADFBrevin; AGEL; Brevin; DKFZp313L0718; Gelsolin; RP11-477J21.1
Gene Aliases: ADF; AGEL; Gsb; GSN
UniProt ID: (Human) P06396, (Rat) Q68FP1, (Mouse) P13020
Entrez Gene ID: (Human) 2934, (Rat) 296654, (Mouse) 227753
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