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Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Non-human primate, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
A synthetic peptide corresponding to a sequence at the C-terminus of human Gelsolin (763-775aa WDDDYWSVDPLDR). |
Conjugate |
Unconjugated |
Form |
Lyophilized |
Concentration |
500 µg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS with 5mg BSA |
Contains |
0.05mg sodium azide, 0.05mg thimerosal |
Storage conditions |
-20°C |
RRID |
AB_2746448 |
Reconstitute with 0.2 ml of distilled water to yield a concentration of 500 µg/ml.
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Actin-depolymerizing factor; ADF; ADFBrevin; AGEL; Brevin; DKFZp313L0718; Gelsolin; RP11-477J21.1
Gene Aliases: ADF; AGEL; Gsb; GSN
UniProt ID: (Human) P06396, (Rat) Q68FP1, (Mouse) P13020
Entrez Gene ID: (Human) 2934, (Rat) 296654, (Mouse) 227753
Molecular Function:
non-motor actin binding protein
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