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Invitrogen

Ghrelin Polyclonal Antibody

View all (28) Ghrelin antibodies

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Ghrelin Polyclonal Antibody

Product Details

PA1-9596

Applications
Tested Dilution
Publications

ELISA (ELISA)

1:500-1:2,000
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Chicken / IgY

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to amino acids 17-28 of human ghrelin.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

200 µg

Purification

Affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2111588

Product Specific Information

PA1-9596 detects Ghrelin in human and mouse samples.

PA1-9596 has been successfully used in ELISA procedures.

PA1-9596 immunogen is a synthetic peptide corresponding to amino acids 17-28 of human ghrelin.

Target Information

GHRL encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an the ligand for the growth hormone secretagogue receptor type 1 and is involved in regulating growth hormone release. Ghrelin has an appeptite-stimulating effect and induces adiposity and stimulates gastric acid secretion. Obestatin may be the ligand for the orphan G protein-coupled receptor GPR39 and is involved in satiety and can have an appetite-reducing effect resulting in decreased food intake.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: AMCBX1; Appetite-regulating hormone; appetite-regulating hormone isoform In2c; FIP-3; FIP3; Fip3p; ghrelin 27; ghrelin 28; ghrelin, growth hormone secretagogue receptor ligand; ghrelin/obestatin; ghrelin/obestatin preprohormone; ghrelin/obestatin prepropeptide; Growth hormone secretagogue; Growth hormone-releasing peptide; IKK-gamma; In2c-preproghrelin; IP; IP1; IP2; IPD2; Motilin-related peptide; NEMO; OTTHUMP00000207794; OTTHUMP00000207795; OTTHUMP00000207796; OTTHUMP00000207798; prepro-appetite regulatory hormone; preproghrelin; proghrelin; Protein M46

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Gene Aliases: 2210006E23Rik; Ghr; GHRL; m46; MTLRP; MTLRPAP; UNQ524/PRO1066

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UniProt ID: (Human) Q9UBU3, (Mouse) Q9EQX0

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Entrez Gene ID: (Human) 51738, (Mouse) 58991

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Function(s)
G-protein coupled receptor binding hormone activity protein binding growth hormone-releasing hormone activity protein tyrosine kinase activator activity ghrelin receptor binding peptide hormone
Process(es)
gastric acid secretion negative regulation of endothelial cell proliferation G-protein coupled receptor internalization glucose metabolic process G-protein coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration synapse assembly actin polymerization or depolymerization adult feeding behavior response to hormone hormone-mediated signaling pathway dendrite development negative regulation of angiogenesis growth hormone secretion response to nutrient levels positive regulation of insulin secretion regulation of response to food positive regulation of response to food positive regulation of appetite negative regulation of interleukin-1 beta production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production positive regulation of insulin secretion involved in cellular response to glucose stimulus positive regulation of growth rate negative regulation of locomotion positive regulation of multicellular organism growth regulation of cell proliferation negative regulation of circadian sleep/wake cycle, REM sleep negative regulation of apoptotic process cortisol secretion positive regulation of MAPK cascade response to estrogen positive regulation of growth positive regulation of circadian sleep/wake cycle, non-REM sleep negative regulation of insulin secretion decidualization negative regulation of inflammatory response cartilage development positive regulation of corticotropin secretion positive regulation of cortisol secretion response to electrical stimulus positive regulation of synapse assembly regulation of transmission of nerve impulse excitatory postsynaptic potential positive regulation of growth hormone secretion positive regulation of growth hormone receptor signaling pathway postsynaptic modulation of chemical synaptic transmission regulation of postsynapse organization positive regulation of small intestinal transit positive regulation of cold-induced thermogenesis positive regulation of bone development positive regulation of sprouting angiogenesis positive regulation of eating behavior positive regulation of adipose tissue development positive regulation of gastro-intestinal system smooth muscle contraction positive regulation of gastric mucosal blood circulation positive regulation of small intestine smooth muscle contraction regulation of gastric motility positive regulation of vascular endothelial cell proliferation positive regulation of feeding behavior activation of MAPK activity visual learning negative regulation of tumor necrosis factor biosynthetic process negative regulation of interleukin-6 biosynthetic process positive regulation of protein tyrosine kinase activity negative regulation of energy homeostasis positive regulation of energy homeostasis
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