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Invitrogen

Ghrelin Polyclonal Antibody

View all (14) Ghrelin antibodies
635D49A6-4B57-425E-8DC4-6BA1AEB7B473 Created with sketchtool. Datasheet
433BB748-DC81-4FE4-83AD-384F97313745 Created with sketchtool. Create Citation
C488C313-B559-4BFD-B17D-A8B65492815A Created with sketchtool. Tech Support
635D49A6-4B57-425E-8DC4-6BA1AEB7B473 Created with sketchtool. Datasheet
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C488C313-B559-4BFD-B17D-A8B65492815A Created with sketchtool. Tech Support

Product Details

Tested Applications
Dilution
Immunocytochemistry (ICC)
Assay Dependent
Immunofluorescence (IF)
Assay Dependent
Immunohistochemistry (IHC)
2 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
2-5 µg/mL
Product Specifications
Species Reactivity
Human, Rat
Host / Isotype
Goat / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (QDILWEEAKEAPADK) corresponding to the C-terminus amino acids of GHRL
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_10984283

Target Information

GHRL encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an the ligand for the growth hormone secretagogue receptor type 1 and is involved in regulating growth hormone release. Ghrelin has an appeptite-stimulating effect and induces adiposity and stimulates gastric acid secretion. Obestatin may be the ligand for the orphan G protein-coupled receptor GPR39 and is involved in satiety and can have an appetite-reducing effect resulting in decreased food intake.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Appetite-regulating hormone; Ghrelin; ghrelin precursor; ghrelin, growth hormone secretagogue receptor ligand; Ghrelin-27; Ghrelin-28; ghrelin/obestatin; ghrelin/obestatin preprohormone; ghrelin/obestatin prepropeptide; GHRL; Growth hormone secretagogue; Growth hormone-releasing peptide; In2c-preproghrelin; Motilin-related peptide; MTLRP; Obestatin; Obestatin-13; Obestatin-23; OTTHUMP00000207794; OTTHUMP00000207795; OTTHUMP00000207796; OTTHUMP00000207798; prepro-appetite regulatory hormone; preproghrelin; Protein M46

Gene Aliases: GHRL; MTLRP; UNQ524/PRO1066

UniProt ID: (Human) Q9UBU3, (Rat) Q9QYH7

Entrez Gene ID: (Human) 51738, (Rat) 59301

Function(s)
activation of MAPK activity gastric acid secretion negative regulation of endothelial cell proliferation G-protein coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration actin polymerization or depolymerization adult feeding behavior response to hormone hormone-mediated signaling pathway dendrite development positive regulation of insulin secretion regulation of response to food positive regulation of response to food positive regulation of appetite negative regulation of interleukin-1 beta production negative regulation of locomotion regulation of cell proliferation negative regulation of circadian sleep/wake cycle, REM sleep negative regulation of tumor necrosis factor biosynthetic process negative regulation of apoptotic process response to estrogen negative regulation of interleukin-6 biosynthetic process positive regulation of circadian sleep/wake cycle, non-REM sleep negative regulation of insulin secretion decidualization negative regulation of inflammatory response positive regulation of corticotropin secretion positive regulation of cortisol secretion positive regulation of synapse assembly excitatory postsynaptic potential positive regulation of growth hormone secretion positive regulation of protein tyrosine kinase activity negative regulation of energy homeostasis positive regulation of energy homeostasis glucose metabolic process negative regulation of angiogenesis growth hormone secretion positive regulation of multicellular organism growth cortisol secretion cartilage development positive regulation of growth hormone receptor signaling pathway
Process(es)
G-protein coupled receptor binding protein binding growth hormone-releasing hormone activity protein tyrosine kinase activator activity ghrelin receptor binding hormone activity

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