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Immunofluorescent analysis of Glucocorticoid Receptor using Glucocorticoid Receptor Polyclonal Antibody (Product# PA1-511A ) shows staining in NIH-3T3 Cells. Glucocorticoid Receptor (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with an antibody recognizing Glucocorticoid Receptor (Product# PA1-511A ) at a dilution of 1:20 over night at 4 °C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody (Product# 35552 for GAR, Product# 35503 for GAM). Images were taken at 60X magnification.
|Tested species reactivity||Human, Mouse, Rat|
|Published species reactivity||Rabbit, Yeast, Rat, Primate, Bovine, Sheep, Mouse, Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues D(346) Q K P I F N V I P P I P V G S E N W N R C(367) from human GR.|
|Purification||Antigen affinity chromatography|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||1 µg/ml|
|Immunohistochemistry (Paraffin) (IHC (P))||1:200|
|Western Blot (WB)||5 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|ChIP assay (ChIP)||See 9 publications below|
|Western Blot (WB)||See 30 publications below|
|Immunocytochemistry (ICC)||See 7 publications below|
|Immunoprecipitation (IP)||See 3 publications below|
|Immunohistochemistry (IHC)||See 14 publications below|
|Blocking Assay (BLOCK)||See 1 publications below|
|Gel Shift (GS)||See 1 publications below|
PA1-511A detects glucocorticoid receptor (GR) from human, mouse and rat tissues.
PA1-511A has been successfully used in Western blot, immunocytochemistry, immunofluorescence, and immunohistochemistry procedures. By Western blot, this antibody detects an ~97 kDa protein representing GR from rat liver extract. Immunocytochemical staining of GR in HeLa cells using PA1-511A results in cytoplasmic staining in the absence of ligand, and nuclear staining after hormone administration.
The PA1-511A immunogen is a synthetic peptide corresponding to residues D(346) Q K P I F N V I P P I P V G S E N W N R C(367) from human GR. The PA1-511A immunizing peptide (Cat. # PEP-001) is available for use in neutralization and control experiments.
Steroid receptors are ligand-dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Glucocorticoids are a family of steroids necessary for the regulation of energy metabolism and the immune and inflammatory responses. These compounds exert their effect through their interaction with the glucocoticoid receptor (GR) and that complex's subsequent association with DNA. All normal mammalian tissues examined to date have been shown to contain glucocorticoid receptor.
The corresponding gene for the glucocoritcoid receptor is NR3C1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Dynamics of chromatin accessibility and long-range interactions in response to glucocorticoid pulsing.
PA1-511A was used in ChIP assay to study the effect of pulsatile hormone stimulations on gene and regulatory element activation
|Stavreva DA,Coulon A,Baek S,Sung MH,John S,Stixova L,Tesikova M,Hakim O,Miranda T,Hawkins M,Stamatoyannopoulos JA,Chow CC,Hager GL||Genome research (25:845)||2015|
A structural explanation of the effects of dissociated glucocorticoids on glucocorticoid receptor transactivation.
PA1-511A was used in ChIP assay to study the structural basis for the glucocorticoid receptor activity of the dissociated glucocorticoids RU24782 and RU24858
|Dezitter X,Fagart J,Taront S,Fay M,Masselot B,Hétuin D,Formstecher P,Rafestin-Oblin ME,Idziorek T||Molecular pharmacology (85:226)||2014|
Regulation of hypothalamic corticotropin-releasing hormone transcription by elevated glucocorticoids.
PA1-511A was used in ChIP assay to study the mechanism by which elevated glucocorticoid levels transcriptionally regulate hypothalamic corticotropin-releasing hormone production
|Evans AN,Liu Y,Macgregor R,Huang V,Aguilera G||Molecular endocrinology (Baltimore, Md.) (27:1796)||2013|
Brain-derived neurotrophic factor signaling rewrites the glucocorticoid transcriptome via glucocorticoid receptor phosphorylation.
PA1-511A was used in ChIP assay to study the role of glucocorticoid receptor phosphorylation in the mechanism by which BDNF modulates the glucocorticoid transcriptome
|Lambert WM,Xu CF,Neubert TA,Chao MV,Garabedian MJ,Jeanneteau FD||Molecular and cellular biology (33:3700)||2013|
Reprogramming the chromatin landscape: interplay of the estrogen and glucocorticoid receptors at the genomic level.
PA1-511A was used in ChIP assay to study the role of chromatin reorganization in the genomic level interactions between the estrogen and glucocorticoid receptors
|Miranda TB,Voss TC,Sung MH,Baek S,John S,Hawkins M,Grøntved L,Schiltz RL,Hager GL||Cancer research (73:5130)||2013|
Separate regions of glucocorticoid receptor, coactivator TIF2, and comodulator STAMP modify different parameters of glucocorticoid-mediated gene induction.
PA1-511A was used in ChIP assay to study the role of different regions of the glucocorticid receptor in glucocorticoid-mediated gene expression
|Awasthi S,Simons SS||Molecular and cellular endocrinology (355:121)||2012|
DNA methylation status predicts cell type-specific enhancer activity.
PA1-511A was used in ChIP assay to study the effect of DNA methylation on cell type-specific enhancer activity
|Wiench M,John S,Baek S,Johnson TA,Sung MH,Escobar T,Simmons CA,Pearce KH,Biddie SC,Sabo PJ,Thurman RE,Stamatoyannopoulos JA,Hager GL||The EMBO journal (30:3028)||2011|
Transcription factor AP1 potentiates chromatin accessibility and glucocorticoid receptor binding.
PA1-511A was used in ChIP assay to investigate the importance of AP1 in GR-mediated transcriptional regulation
|Biddie SC,John S,Sabo PJ,Thurman RE,Johnson TA,Schiltz RL,Miranda TB,Sung MH,Trump S,Lightman SL,Vinson C,Stamatoyannopoulos JA,Hager GL||Molecular cell (43:145)||2011|
Extensive chromatin remodelling and establishment of transcription factor 'hotspots' during early adipogenesis.
PA1-511A was used in ChIP assay to investigate the changes of chromatin structure in early adipogenesis
|Siersbæk R,Nielsen R,John S,Sung MH,Baek S,Loft A,Hager GL,Mandrup S||The EMBO journal (30:1459)||2011|
The influence of combined oral contraceptives containing drospirenone on hypothalamic-pituitary-adrenocortical axis activity and glucocorticoid receptor expression and function in women with polycystic ovary syndrome.
PA1-511A was used in western blot to test if oral contraceptives modulate glucocorticoid receptor expression and function in patients with PCOS
|Macut D,Božić Antić I,Nestorov J,Topalović V,Bjekić Macut J,Panidis D,Kastratović Kotlica B,Papadakis E,Matić G,Vojnović Milutinović D||Hormones (Athens, Greece) (14:109)||2015|
High-fructose diet leads to visceral adiposity and hypothalamic leptin resistance in male rats--do glucocorticoids play a role?
PA1-511A was used in western blot to study the role of altered glucocorticoid signaling in the mechanism by which a high-fructose diet induces visceral adipose accumulation and hypothalmic resistance to leptin
|Bursać BN,Vasiljević AD,Nestorović NM,Veličković NA,Vojnović Milutinović DD,Matić GM,Djordjevic AD||The Journal of nutritional biochemistry (25:446)||2014|
Enhanced prereceptor glucocorticoid metabolism and lipogenesis impair insulin signaling in the liver of fructose-fed rats.
PA1-511A was used in western blot to study the hepatic effects of a high fructose diet on pre-receptor glucocorticid metabolism, lipid metabolism and insulin signaling in a rat model
|Vasiljević A,Veličković N,Bursać B,Djordjevic A,Milutinović DV,Nestorović N,Matić G||The Journal of nutritional biochemistry (24:1790)||2013|
Lymphocyte glucocorticoid receptor expression level and hormone-binding properties differ between war trauma-exposed men with and without PTSD.
PA1-511A was used in western blot to study glucocorticoid receptor expression and function in men with or without post traumatic stress disorder following exposure to war trauma
|Matić G,Milutinović DV,Nestorov J,Elaković I,Jovanović SM,Perišić T,Dunđerski J,Damjanović S,Knežević G,Špirić Ž,Vermetten E,Savić D||Progress in neuro-psychopharmacology & biological psychiatry (43:238)||2013|
Fructose consumption enhances glucocorticoid action in rat visceral adipose tissue.
PA1-511A was used in western blot to study the enhancement of the effects of glucocorticoids on rat visceral adipose tissue by the prolonged consumption of fructose
|Bursać BN,Djordjevic AD,Vasiljević AD,Milutinović DD,Veličković NA,Nestorović NM,Matić GM||The Journal of nutritional biochemistry (24:1166)||2013|
Time-course of hypothalamic-pituitary-adrenal axis activity and inflammation in juvenile rat brain after cranial irradiation.
PA1-511A was used in western blot to study the time-course of the inflammatory response and activation of the hypothalamic axis in response to cranial irradiation
|Veličković N,Drakulić D,Petrović S,Grković I,Milošević M,Stanojlović M,Horvat A||Cellular and molecular neurobiology (32:1175)||2012|
Hypothalamic-pituitary-adrenocortical axis hypersensitivity and glucocorticoid receptor expression and function in women with polycystic ovary syndrome.
PA1-511A was used in western blot to investigate the molecular mechanisms responsible for the pathogenesis of polycystic ovary syndrome
|Milutinović DV,Macut D,Božić I,Nestorov J,Damjanović S,Matić G||Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association (119:636)||2011|
Identification of a lysosomal pathway that modulates glucocorticoid signaling and the inflammatory response.
PA1-511A was used in western blot to study a lysosomal pathway that modulates glucocorticoid signaling and the inflammatory response
|He Y,Xu Y,Zhang C,Gao X,Dykema KJ,Martin KR,Ke J,Hudson EA,Khoo SK,Resau JH,Alberts AS,MacKeigan JP,Furge KA,Xu HE||Science signaling (4:null)||2011|
Gender-specific response of brain corticosteroid receptors to stress and fluoxetine.
PA1-511A was used in western blot to investigate the effect of stress and fluoxetine on brain corticosteroid receptors between sexes
|Elaković I,Djordjevic A,Adzic M,Djordjevic J,Radojčić M,Matić G||Brain research (1384:61)||2011|
Glucocorticoids activate Epstein Barr virus lytic replication through the upregulation of immediate early BZLF1 gene expression.
PA1-511A was used in western blot to investigate the mechanism for the effect of glucocorticoids on Epstein Barr virus lytic replication
|Yang EV,Webster Marketon JI,Chen M,Lo KW,Kim SJ,Glaser R||Brain, behavior, and immunity (24:1089)||2010|
Differentiating intraocular glucocorticoids.
PA1-511A was used in western blot to investigate the application of glucocorticoids in the treatment of ocular diseases
|Edelman JL||Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fu¿r Augenheilkunde (224 Suppl 1:25)||2010|
Regular exercise prevents the development of hyperglucocorticoidemia via adaptations in the brain and adrenal glands in male Zucker diabetic fatty rats.
PA1-511A was used in western blot to study the mechanism for the preventive effect of exercise on hyperglucocorticoidemia
|Campbell JE,Király MA,Atkinson DJ,D'souza AM,Vranic M,Riddell MC||American journal of physiology. Regulatory, integrative and comparative physiology (299:R168)||2010|
The effect of restraint stress on glucocorticoid receptors in mouse spleen lymphocytes: involvement of the sympathetic nervous system.
PA1-511A was used in western blot to investigate the influence of restraint stress on specific gene expression in spleen lymphocytes
|Warner A,Ovadia H,Tarcic N,Weidenfeld J||Neuroimmunomodulation (17:298)||2010|
Sexually dimorphic functional alterations of rat hepatic glucocorticoid receptor in response to fluoxetine.
PA1-511A was used in western blot to investigate the influence of fluoxetine on glucocorticoid receptor function in livers of rats
|Elaković I,Vasiljević D,Adzic M,Djordjevic A,Djordjevic J,Radojcić M,Matić G||European journal of pharmacology (632:79)||2010|
Cranial irradiation modulates hypothalamic-pituitary-adrenal axis activity and corticosteroid receptor expression in the hippocampus of juvenile rat.
PA1-511A was used in western blot to investigate the effect of cranial irradiation on activation of HPA axis and corticosteroid receptor expression in juvenile rat hippocampus
|Velickovic N,Djordjevic A,Drakulic D,Stanojevic I,Secerov B,Horvat A||General physiology and biophysics (28 Spec No:219)||2009|
Bovine intramuscular, subcutaneous, and perirenal stromal-vascular cells express similar glucocorticoid receptor isoforms, but exhibit different adipogenic capacity.
PA1-511A was used in western blot to investigate the expression and function of glucocorticoid receptor isoforms in various bovine stromal-vascular cells
|Ortiz-Colón G,Grant AC,Doumit ME,Buskirk DD||Journal of animal science (87:1913)||2009|
Gender-related differences in the effects of antidepressant imipramine on glucocorticoid receptor binding properties and association with heat shock proteins in the rat liver and kidney.
PA1-511A was used in western blot to study the gender-dependent responses to imipramine treatment and its mechanism
|Elaković I,Brkljacić J,Matić G||European journal of pharmacology (608:7)||2009|
Combinatorial probabilistic chromatin interactions produce transcriptional heterogeneity.
PA1-511A was used in western blot to investigate the mechanism for probabilistic process of gene expression at the single-cell level.
|Voss TC,Schiltz RL,Sung MH,Johnson TA,John S,Hager GL||Journal of cell science (122:345)||2009|
Expression and distribution of glucocorticoid receptors in the ovine fetal adrenal cortex: effect of long-term hypoxia.
PA1-511A was used in western blot to examine the effect of long-term hypoxia on the expression of GR in the ovine fetal adrenal cortex
|Root B,Abrassart J,Myers DA,Monau T,Ducsay CA||Reproductive sciences (Thousand Oaks, Calif.) (15:517)||2008|
Long-term hypoxia modulates expression of key genes regulating adrenomedullary function in the late gestation ovine fetus.
PA1-511A was used in western blot to study the effect of long-term hypoxia on the expression of select genes in ovine fetus during late gestation
|Ducsay CA,Hyatt K,Mlynarczyk M,Root BK,Kaushal KM,Myers DA||American journal of physiology. Regulatory, integrative and comparative physiology (293:R1997)||2007|
Long-term imipramine treatment affects rat brain and pituitary corticosteroid receptors and heat shock proteins levels in a gender-specific manner.
PA1-511A was used in western blot to study the sex-dependent effect of imipramine treatment on rat brain and pituitary corticosteroid receptors and heat shock proteins levels
|Elaković I,Brkljacić J,Matić G||Journal of neural transmission (Vienna, Austria : 1996) (114:1069)||2007|
Analysis of the bovine neutrophil transcriptome during glucocorticoid treatment.
PA1-511A was used in western blot to analyze bovine neutrophil transcriptome during anti-inflammatory glucocorticoid dexamethasone (Dex) treatment
|Weber PS,Madsen-Bouterse SA,Rosa GJ,Sipkovsky S,Ren X,Almeida PE,Kruska R,Halgren RG,Barrick JL,Burton JL||Physiological genomics (28:97)||2006|
Glucocorticoid receptor and nuclear factor-kappa B interactions in restraint stress-mediated protection against acoustic trauma.
PA1-511A was used in western blot to study the interaction between glucocorticoid receptor and nuclear factor kappa B during acoustic trauma.
|Tahera Y,Meltser I,Johansson P,Hansson AC,Canlon B||Endocrinology (147:4430)||2006|
Cortisol and its action on the glucocorticoid receptor in malnutrition and acute infection.
PA1-511A was used in western blot to study the role of cortisol in malnutrition and acute infection and its mechanism
|Manary MJ,Muglia LJ,Vogt SK,Yarasheski KE||Metabolism: clinical and experimental (55:550)||2006|
Effects of glucocorticoids on Fas gene expression in bovine blood neutrophils.
PA1-511A was used in western blot to study the mechanism for the anti-apoptotic effects of glucocorticoids in bovine blood neutrophils
|Chang LC,Madsen SA,Toelboell T,Weber PS,Burton JL||The Journal of endocrinology (183:569)||2004|
A glucocorticoid/retinoic acid receptor chimera that displays cytoplasmic/nuclear translocation in response to retinoic acid. A real time sensing assay for nuclear receptor ligands.
PA1-511A was used in western blot to study the effect of retinoic acid on cytoplasmic/nuclear translocation.
|Mackem S,Baumann CT,Hager GL||The Journal of biological chemistry (276:45501)||2001|
Glucocorticoid receptor structure and function in an adrenocorticotropin-secreting small cell lung cancer.
PA1-511A was used in western blot to characterize glucocorticoid receptor in DMS-79 cells
|Gaitan D,DeBold CR,Turney MK,Zhou P,Orth DN,Kovacs WJ||Molecular endocrinology (Baltimore, Md.) (9:1193)||1995|
Heat shock protein hsp90 regulates dioxin receptor function in vivo.
PA1-511A was used in western blot to investigate the role of heat shock protein hsp90 on dioxin receptor function in vivo
|Whitelaw ML,McGuire J,Picard D,Gustafsson JA,Poellinger L||Proceedings of the National Academy of Sciences of the United States of America (92:4437)||1995|
Ligand-dependent down-regulation of stably transfected human glucocorticoid receptors is associated with the loss of functional glucocorticoid responsiveness.
PA1-511A was used in western blot to investigate the regulation of stably transfected human glucocorticoid receptors by glucocorticoids
|Bellingham DL,Sar M,Cidlowski JA||Molecular endocrinology (Baltimore, Md.) (6:2090)||1992|
Novel antipeptide antibodies to the human glucocorticoid receptor: recognition of multiple receptor forms in vitro and distinct localization of cytoplasmic and nuclear receptors.
PA1-511A was used in western blot to produce novel antibodies specifically recognizing human GR
|Cidlowski JA,Bellingham DL,Powell-Oliver FE,Lubahn DB,Sar M||Molecular endocrinology (Baltimore, Md.) (4:1427)||1990|
Development of an assay to measure mutagenic non-homologous end-joining repair activity in mammalian cells.
PA1-511A was used in immunocytochemistry to build and validate an assay capable of measuring mutagenic non-homologous end-joining repair activity in mammalian cells
|Bindra RS,Goglia AG,Jasin M,Powell SN||Nucleic acids research (41:null)||2013|
Prenatal dexamethasone impairs behavior and the activation of the BDNF exon IV promoter in the paraventricular nucleus in adult offspring.
PA1-511A was used in immunocytochemistry to investigate the influence of prenatal dexamethasone treatment on adult rat offspring
|Hossain A,Hajman K,Charitidi K,Erhardt S,Zimmermann U,Knipper M,Canlon B||Endocrinology (149:6356)||2008|
Differential effects of RU486 reveal distinct mechanisms for glucocorticoid repression of prostaglandin E release.
PA1-511A was used in immunocytochemistry to study the mechanisms for the effect of glucocorticoids on prostaglandin E release
|Chivers JE,Cambridge LM,Catley MC,Mak JC,Donnelly LE,Barnes PJ,Newton R||European journal of biochemistry / FEBS (271:4042)||2004|
Differential effects of adrenalectomy on melanin-concentrating hormone and orexin A.
PA1-511A was used in immunocytochemistry to investigate the mechanism of glucocorticoid-promoted food intake.
|Drazen DL,Coolen LM,Strader AD,Wortman MD,Woods SC,Seeley RJ||Endocrinology (145:3404)||2004|
Liganded androgen receptor interaction with beta-catenin: nuclear co-localization and modulation of transcriptional activity in neuronal cells.
PA1-511A was used in immunocytochemistry to investigate the association between beta-catenin and androgen receptor.
|Pawlowski JE,Ertel JR,Allen MP,Xu M,Butler C,Wilson EM,Wierman ME||The Journal of biological chemistry (277:20702)||2002|
Localization of the glucocorticoid receptor in discrete clusters in the cell nucleus.
PA1-511A was used in immunocytochemistry to investigate the localization of the glucocorticoid receptor in the cell nucleus
|van Steensel B,Brink M,van der Meulen K,van Binnendijk EP,Wansink DG,de Jong L,de Kloet ER,van Driel R||Journal of cell science (108 ( Pt 9):3003)||1995|
|Rat||1:5,000 or 1:1,000||
Immunocytochemical localization of the glucocorticoid receptor in rat brain, pituitary, liver, and thymus with two new polyclonal antipeptide antibodies.
PA1-511A was used in immunocytochemistry to investigate the distribution of glucocorticoid receptor in various rat tissues
|McGimsey WC,Cidlowski JA,Stumpf WE,Sar M||Endocrinology (129:3064)||1991|
Expression and regulation of human fetal-specific CYP3A7 in mice.
PA1-511A was used in immunoprecipitation to investigate the expression of CYP3A7 and its regulation mechanism in fetal liver
|Pang XY,Cheng J,Kim JH,Matsubara T,Krausz KW,Gonzalez FJ||Endocrinology (153:1453)||2012|
BDNF and glucocorticoids regulate corticotrophin-releasing hormone (CRH) homeostasis in the hypothalamus.
PA1-511A was used in immunoprecipitation to investigate the effect of BDNF and glucocorticoids on CRH regulation in the hypothalamus
|Jeanneteau FD,Lambert WM,Ismaili N,Bath KG,Lee FS,Garabedian MJ,Chao MV||Proceedings of the National Academy of Sciences of the United States of America (109:1305)||2012|
Chromatin accessibility pre-determines glucocorticoid receptor binding patterns.
PA1-511A was used in immunoprecipitation to investigate the effect of chromatin structure on glucocorticoid receptor binding
|John S,Sabo PJ,Thurman RE,Sung MH,Biddie SC,Johnson TA,Hager GL,Stamatoyannopoulos JA||Nature genetics (43:264)||2011|
Distribution and subcellular localization of glucocorticoid receptor-immunoreactive neurons in the developing and adult male zebra finch brain.
PA1-511A was used in immunohistochemistry to characterize the glucocorticoid receptor-immunoreactive neurons in male zebra finch brain
|Shahbazi M,Schmidt M,Carruth LL||General and comparative endocrinology (174:354)||2011|
Expression of the glucocorticoid receptor in renal cell neoplasms: an immunohistochemical and quantitative reverse transcriptase polymerase chain reaction study.
PA1-511A was used in immunohistochemistry to study the glucocorticoid receptor expression in renal cell neoplasms
|Yakirevich E,Matoso A,Sabo E,Wang LJ,Tavares R,Meitner P,Morris DJ,Pareek G,Delellis RA,Resnick MB||Human pathology (42:1684)||2011|
Expression of glucocorticoid receptor and early growth response gene 1 during postnatal development of two inbred strains of mice exposed to early life stress.
PA1-511A was used in immunohistochemistry to investigate the effect of early life stress on the expression of glucocorticoid receptor and early growth response gene 1
|Navailles S,Zimnisky R,Schmauss C||Developmental neuroscience (32:139)||2010|
Estrogen receptor beta activation prevents glucocorticoid receptor-dependent effects of the central nucleus of the amygdala on behavior and neuroendocrine function.
PA1-511A was used in immunohistochemistry to study the effects of estrogen receptor beta on behavior and neuroendocrine function
|Weiser MJ,Foradori CD,Handa RJ||Brain research (1336:78)||2010|
Prostaglandin treatment is associated with a withdrawal of progesterone and androgen at the receptor level in the uterine cervix.
PA1-511A was used in immunohistochemistry to investigate the mechanism of the prostaglandin treatment for cervical priming
|Vladic-Stjernholm Y,Vladic T,Blesson CS,Ekman-Ordeberg G,Sahlin L||Reproductive biology and endocrinology : RB&E (7:null)||2009|
Potential role of glucocorticoid signaling in the formation of pancreatic islets in the human fetus.
PA1-511A was used in immunohistochemistry to study the role of glucocorticoid receptor in the development of pancreatic islets
|Phan-Hug F,Guimiot F,Lelièvre V,Delezoide AL,Czernichow P,Breant B,Blondeau B||Pediatric research (64:346)||2008|
Altered hypothalamus-pituitary-adrenal gland axis regulation in the expanded CGG-repeat mouse model for fragile X-associated tremor/ataxia syndrome.
PA1-511A was used in immunohistochemistry to examine the status of hypothalamus-pituitary-adrenal gland axis in fragile X-associated tremor/ataxia syndrome
|Brouwer JR,Severijnen E,de Jong FH,Hessl D,Hagerman RJ,Oostra BA,Willemsen R||Psychoneuroendocrinology (33:863)||2008|
Steroid receptor expression and morphology in provoked vestibulodynia.
PA1-511A was used in immunohistochemistry to investigate the expression of steroid receptor in vulvar vestibular mucosa
|Johannesson U,Sahlin L,Masironi B,Hilliges M,Blomgren B,Rylander E,Bohm-Starke N||American journal of obstetrics and gynecology (198:311.e1)||2008|
Differential expression of glucocorticoid receptor in carcinomas of the human digestive system.
PA1-511A was used in immunohistochemistry to investigate the expression of glucocorticoid receptor in carcinomas of human digestive system
|Lien HC,Lu YS,Shun CT,Yao YT,Chang WC,Cheng AL||Histopathology (52:314)||2008|
Steroid receptor expression in the vulvar vestibular mucosa--effects of oral contraceptives and menstrual cycle.
PA1-511A was used in immunohistochemistry to study the expression of steroid receptor in the vulvar vestibular mucosa after the intake of oral contraceptives and during menstrual cycle
|Johannesson U,Sahlin L,Masironi B,Rylander E,Bohm-Starke N||Contraception (76:319)||2007|
Distribution of glucocorticoid receptor alpha and beta subtypes in the idiopathic inflammatory myopathies.
PA1-511A was used in immunohistochemistry and western blot to study the distribution of glucocorticoid receptor alpha and beta subtypes in idiopathic inflammatory myopathies
|De Bleecker JL,De Paepe B,Vervaet VL,Arys B,Creus KK,Werbrouck BF,Martin JJ||Neuromuscular disorders : NMD (17:186)||2007|
Glucocorticoid receptor expression in advanced non-small cell lung cancer: clinicopathological correlation and in vitro effect of glucocorticoid on cell growth and chemosensitivity.
PA1-511A was used in immunohistochemistry to study the expression and role of glucocorticoid receptor expression in advanced non-small cell lung cancer
|Lu YS,Lien HC,Yeh PY,Kuo SH,Chang WC,Kuo ML,Cheng AL||Lung cancer (Amsterdam, Netherlands) (53:303)||2006|
Factors involved in the inflammatory events of cervical ripening in humans.
PA1-511A was used in immunohistochemistry to study the potential role of altered glucocorticoid responses in the inflammatory events associated with human cervical ripening
|Stjernholm-Vladic Y,Stygar D,Mansson C,Masironi B,Akerberg S,Wang H,Ekman-Ordeberg G,Sahlin L||Reproductive biology and endocrinology : RB&E (2:null)||2004|
Glucocorticoids act in the dorsal hindbrain to increase arterial pressure.
PA1-511A was used in immunohistochemistry to investigate the role of glucocorticoids in the dorsal hindbrain of rat
|Scheuer DA,Bechtold AG,Shank SS,Akana SF||American journal of physiology. Heart and circulatory physiology (286:H458)||2004|
Progesterone receptors, oestrogen receptor alpha and glucocorticoid receptors in the bovine intercaruncular uterine wall around parturition.
PA1-511A was used in blocking or activating experiment to examine the status of steroid hormone receptors in the bovine intercaruncular uterine wall around parturition
|Schäubli M,Ritter N,Hässig M,Zerbe H,Bleul U,Boos A||Animal reproduction science (103:215)||2008|
Heterodimerization between mineralocorticoid and glucocorticoid receptor: a new principle of glucocorticoid action in the CNS.
PA1-511A was used in EMSA assay to investigate the interaction between glucocorticoid receptor and mineralocorticoid receptor
|Trapp T,Rupprecht R,Castrén M,Reul JM,Holsboer F||Neuron (13:1457)||1994|
GCCR; GCR; glucocorticoid nuclear receptor variant 1; glucocorticoid receptor; glucocorticoid receptor 1; Glucocorticoid receptor lymphocyte; GRL; Grl1; NR3C1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
GCCR; GCR; GCRST; GR; GRL; Grl-1; Grl1; NR3C1