Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA1-122
| Applications | Tested Dilution | Publications |
|---|---|---|
Immunohistochemistry (IHC) |
- | View 4 publications 4 publications |
Immunohistochemistry (Frozen) (IHC (F)) |
1 µg/mL | - |
Immunohistochemistry - Free Floating (IHC (Free)) |
- | View 1 publication 1 publication |
| Product Specifications | |
|---|---|
Species Reactivity |
Mouse |
Published species |
Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic peptide corresponding to residues pyroE(22) H W S Y G L R P G-NH2(32) of mouse GnRH. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS with 1mg/mL BSA |
Contains |
0.05% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_325014 |
Product Specific Information
PA1-122 detects gonadotropin releasing hormone (GnRH) in mouse brain.
PA1-122 has been successfully used in immunohistochemistry procedures. Immunohistochemical staining of GnRH in newborn mouse brain tissue using PA1-122 results in neuronal staining.
In immunohistochemical procedures, 4% paraformaldehyde or 2% acrolein is recommended as a fixative.
The PA1-122 immunogen is a synthetic peptide corresponding to residues pyroE(22) H W S Y G L R P G-NH2(32) of mouse GnRH. This sequence is completely conserved in rat and tree shrew and is 78% conserved in zebrafish. The PA1-122 immunizing peptide (Cat. # PEP-168) is available for use in neutralization and control experiments.
Target Information
The Luteinizing Hormone Releasing Hormone (LH-RH) is produced in the hypothalamus and influences the release of Luteinizing Hormone in the pituitary gland. LH-RH is also known as Gonadotropin-releasing hormone (Gn-RH).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GnRH-I; Gonadoliberin I; Gonadoliberin-1; gonadotropin releasing hormone 2; Gonadotropin-releasing hormone I; hypogonadal; LH-RH I; Luliberin I; luteinizing hormone releasing hormone; Luteinizing hormone-releasing hormone I; Lutropin; Progonadoliberin I; Progonadoliberin-1; Prolactin release-inhibiting factor 1; Prolactin release-inhibiting factor I
Gene Aliases: Gnrh; Gnrh1; Gnrh2; hpg; LHRH; Lhrh1; Lnrh
UniProt ID: (Mouse) P13562
Entrez Gene ID: (Mouse) 14714
Molecular Function:
peptide hormone
intercellular signal molecule
multicellular organism development
regulation of gene expression
male sex determination
negative regulation of immature T cell proliferation
negative regulation of apoptotic process
response to ethanol
response to steroid hormone
regulation of ovarian follicle development
negative regulation of neuron migration
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support