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GnRHR Polyclonal Antibody
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FIGURE: 1 / 3
GnRHR Antibody (BS-1464R) in IHC (P)
Formalin-fixed and paraffin-embedded rat brain labeled with Rabbit Anti-GnRHR Polyclonal Antibody, Unconjugated(bs-1464R) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated(bs-0295G-Cy3)used at 1:200 dilution for 40 minutes at 37°C.
Product Details
BS-1464R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Goat,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human GnRHR, amino acids 201-328.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5 region and multiple polyA signals in the 3 region have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G-protein coupled receptor; GnRH receptor; gnRH-R; gonadotropin releasing hormone receptor type-I; gonadotropin-releasing hormone (type 1) receptor 1; Gonadotropin-releasing hormone receptor; growth hormone; leutinizing hormone releasing horomone receptor; leutinizing-releasing hormone receptor; Lh-rh receptor; luliberin receptor; type I GnRH receptor; Type I GNRHR1
Gene Aliases: GH1; GNRHR; GNRHR1; GRHR; HH7; LHRHR; LRHR
UniProt ID: (Human) P30968, (Mouse) Q01776, (Rat) P30969
Entrez Gene ID: (Human) 2798, (Goat) 100860755, (Mouse) 14715, (Rat) 81668
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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