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Abnova
ABCC6 Monoclonal Antibody (5D8)
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Product Details
H00000368-M02
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
5D8
Immunogen
ABCC6 (NP_001162, 831 a.a. approximately 930 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: IAEMGSYQEL LQRKGALVCL LDQARQPGDR GEGETEPGTS TKDPRGTSAG RRPELRRERS IKSVPEKDRT TSEAQTEVPL DDPDRAGWPA GKDSIQYGRV
Target Information
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Anthracycline resistance-associated protein; ATP-binding cassette sub-family C member 6; ATP-binding cassette, sub-family C (CFTR/MRP), member 6; MOAT-E; Multi-specific organic anion transporter E; Multidrug resistance-associated protein 6; similar to multidrug resistance protein MRP1; unnamed protein product
Gene Aliases: ABC34; ABCC6; ARA; EST349056; GACI2; MLP1; MOAT-E; MOATE; MRP6; PXE; PXE1; URG7
UniProt ID: (Human) O95255
Entrez Gene ID: (Human) 368
visual perception
response to xenobiotic stimulus
gene expression
ATP transport
inorganic diphosphate transport
cellular phosphate ion homeostasis
response to magnesium ion
ATP metabolic process
carboxylic acid transport
phosphate ion homeostasis
calcium ion homeostasis
transmembrane transport
leukotriene transport
anion transmembrane transport
inhibition of non-skeletal tissue mineralization
response to sodium phosphate
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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