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H4K8ac Polyclonal Antibody
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FIGURE: 1 / 5
H4K8ac Antibody (BS-53133R) in ICC/IF
Mouse NIH3T3 cells were stained with H4K8ac Polyclonal Antibody (cat. No. bs-53133R) and with DAPI. Cells were fixed with 4% formaldehyde for 10’ and blocked with PBS/TX-100 containing 5% normal goat serum and 1% BSA. The cells were immunofluorescently labeled with the H4K8ac antibody (left) diluted 1:500 in blocking solution followed by an anti-rabbit antibody conjugated to Alexa488. The middle panel shows staining of the nuclei with DAPI. A merge of the two stainings is shown on the right.
Product Details
BS-53133R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
Class
Polyclonal
Type
Antibody
Immunogen
Polyclonal antibody raised in rabbit against the region of Human histone H4 containing the acetylated lysine 8 (H4K8ac), using a KLH-conjugated synthetic peptide
Conjugate
Form
Liquid
Concentration
1.2 mg/mL
Amount
50 µg
Purification
Affinity chromatography
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acetyl Histone H4; Acetyl-H4 K8; Acetyl-H4 Lys8; Acetyl-Histone H4 K8; Acetyl-Histone H4 Lys8; H4 histone family, member A; H4 histone family, member E; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4 K8ac; H4K8; H4Lys8ac; HIST1H4; HIST1H4F; HIST2H4; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 1, H4j; histone 2, H4; histone 2, H4a; Histone 4; Histone 4 family, member M; histone 4, H4; histone cluster 1 H4 family member a; histone cluster 1 H4 family member b; histone cluster 1 H4 family member e; histone cluster 1 H4 family member i; histone cluster 1 H4 family member j; histone cluster 1, H4a; histone cluster 1, H4b; histone cluster 1, H4e; histone cluster 1, H4i; histone cluster 1, H4j; histone cluster 2 H4 family member a; histone cluster 2, H4a; Histone Cluster 4; histone cluster 4 H4; histone family member; Histone H4; Histone H4 acetyl; Histone H4A; Histone H4K8; Histone H4K8ac; histone IV, family 2; unnamed protein product
Gene Aliases: dJ160A22.2; FO108; H4; H4-12; H4-16; H4-53; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/N; H4/O; H4/p; H4C1; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4f16; H4F2; H4F2iv; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4M; HIST1H4A; HIST1H4B; HIST1H4C; HIST1H4D; HIST1H4E; HIST1H4F; HIST1H4H; HIST1H4I; HIST1H4J; HIST1H4K; HIST1H4L; Hist1h4m; HIST2H4; HIST2H4A; HIST2H4B; HIST4H4; TEBIVANED2; TEBIVANED3; TEBIVANED4; TEVANED2; TEVANED3; TEVANED4; X04652
UniProt ID: (Human) P62805, (Mouse) P62806, (Mouse) A4QMY0
Entrez Gene ID: (Human) 8359, (Human) 8363, (Human) 8370, (Human) 121504, (Human) 8366, (Human) 8367, (Human) 8294, (Mouse) 326619, (Mouse) 326620, (Mouse) 319158, (Mouse) 97122
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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