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Invitrogen
H6PD Polyclonal Antibody
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FIGURE: 1 / 1
H6PD Antibody (PA5-92977) in WB
Western blot analysis of H6PD in extracts of various cell lines. Samples were incubated with H6PD Polyclonal antibody (Product # PA5-92977) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
Product Details
PA5-92977
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human H6PD (NP_0042762)
Conjugate
Form
Liquid
Concentration
1.23 mg/mL
Amount
123 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: QELQGHVSII LLGATGDLAK KYLWQGLFQL YLDEAGRGHS FSFHGAALTA PKQGQELMAK ALESLSCPKD MAPSHCAEHK DQFLQLSQYR QLKTAEDYQA LNKDIEAQLQ HAGLREAGRI FYFSVPPFAY EDIARNINSS CRPGPGAWLR VVLEKPFGHD HFSAQQLATE LGTFFQEEEM Y; Positive Samples: Mouse liver, Mouse kidney; Cellular Location: Endoplasmic reticulum lumen
Target Information
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a type 2 salivary cysteine peptidase inhibitor. The protein is an S-type cystatin, based on its high level of expression in saliva, tears and seminal plasma. The specific role in these fluids is unclear but antibacterial and antiviral activity is present, consistent with a protective function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 6-phosphogluconolactonase; G6PD, H form; GDH/6PGL endoplasmic bifunctional protein; glucose 1- dehydrogenase; glucose 1-dehydrogenase; glucose dehydrogenase; glucose dehyrogenase; glucose-6-phosphate dehydrogenase 1; glucose-6-phosphate dehydrogenase, salivary
Gene Aliases: AI785303; CORTRD1; G6pd1; G6PDH; GDH; Gpd-1; Gpd1; H6PD; H6PDH
UniProt ID: (Human) O95479, (Mouse) Q8CFX1
Entrez Gene ID: (Human) 9563, (Mouse) 100198, (Rat) 298655
catalytic activity
glucose-6-phosphate dehydrogenase activity
oxidoreductase activity
oxidoreductase activity, acting on CH-OH group of donors
hydrolase activity
6-phosphogluconolactonase activity
carbohydrate binding
glucose 1-dehydrogenase (NAD+) activity
glucose 1-dehydrogenase (NADP+) activity
glucose 1-dehydrogenase [NAD(P)] activity
NADP binding
dehydrogenase
hydrolase
metabolite interconversion enzyme
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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