Immunogen sequence: DEPPTQNQSD LLNKKVICKQ DLECLAFTKL SETSRMETFS PAVGNRIDVM GGSEEEFMKI LDHLEVSCNK PSTNKTMLWN SFQISSGISS KSFKDNDFGI LHETLPEEVG HLSFNSSSSS EANFKLEPNS PMHGGTLLED VVGGRQTTPE SDFNLQALRS RYEALKKSLS KKREESYLSN SQTPERHKPE LSPTPQNVQT DDTLNFLDTC DLHTEHIKPS LRTSIGERKR SLSPLIKFSP VEQRLRTTIA CSLGELPNLK EEDILNKSLD AKEPPSDLTR; Positive Samples: Mouse spleen, Mouse thymus; Cellular Location: Cytoplasm, centrosome, cytoskeleton, microtubule organizing center, spindle
HAUS6 is 1 of 8 subunits of the 390-kDa human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb augmentare, meaning to increase. The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 ; Uehara et al., 2009 ).
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Protein Aliases: dim gamma-tubulin homolog; family with sequence similarity 29, member A; HAUS augmin-like complex subunit 6; HAUS augmin-like complex, subunit 6; likely ortholog of H. sapiens family with sequence similarity 29, member A (FAM29A)
Gene Aliases: 6230416J20Rik; 9830144E06; D4Ertd27e; DGT6; FAM29A; HAUS6; KIAA1574; mKIAA1574
UniProt ID: (Human) Q7Z4H7