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Proteintech
HB9 Polyclonal Antibody
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Product Details
20975-1-AP
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
Homeobox protein HB9 is expressed in lymphoid and pancreatic tissues. It is reported to be Putative transcription factor involved in pancreas development and function. Defects in this gene causes Currarino syndrome. The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. It is also reported that HB9 is strongly expressed in epidermal basal cells of the outer scale face in tarsometatarsal scale skin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homeobox gene HB9; homeobox HB9; Homeobox protein HB9; HOX SCRA1; Motor neuron and pancreas homeobox protein 1
Gene Aliases: HB9; HLXB9; HOXHB9; MNR2; MNX1; SCRA1
UniProt ID: (Human) P50219
Entrez Gene ID: (Human) 3110, (Mouse) 15285
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
sequence-specific double-stranded DNA binding
sequence-specific DNA binding
helix-turn-helix transcription factor
homeodomain transcription factor
DNA-binding transcription factor
gene-specific transcriptional regulator
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
central nervous system development
spinal cord motor neuron cell fate specification
endocrine pancreas development
neuron projection morphogenesis
neuron migration
transcription, DNA-templated
motor neuron axon guidance
post-embryonic development
nerve development
dorsal/ventral neural tube patterning
central nervous system neuron differentiation
neuron differentiation
pancreas development
cell morphogenesis involved in neuron differentiation
diaphragm development
respiratory system development
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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