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Invitrogen
HBB Polyclonal Antibody
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Product Details
PA5149846
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Chicken,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Hemoglobin Beta (HBb) (Met1-His147)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon-gamma-G-gamma-A-delta-beta-3'.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: beta globin; beta globin chain; Beta-1-globin; Beta-globin; Hb Monza protein; HBB; hemoglobin; hemoglobin beta; Hemoglobin beta chain; hemoglobin beta chain complex; Hemoglobin beta chain, major-form; hemoglobin beta subunit; Hemoglobin beta-1 chain; Hemoglobin subunit beta; Hemoglobin subunit beta-1; hemoglobin, beta; III beta-1 globin; III beta-2 globin; sickle beta-hemoglobin; unnamed protein product; unstable hemoglobin; hemoglobin 'Louisville'
Gene Aliases: beta-globin; CD113t-C; ECYT6; HBB
UniProt ID: (Human) P68871, (Rat) P02091
Entrez Gene ID: (Human) 3043, (Rat) 24440
glutathione metabolic process
regulation of eIF2 alpha phosphorylation by heme
oxygen transport
hemopoiesis
erythrocyte development
protein heterooligomerization
inflammatory response
regulation of blood pressure
carbon dioxide transport
nitric oxide transport
response to hydrogen peroxide
hydrogen peroxide catabolic process
positive regulation of nitric oxide biosynthetic process
renal absorption
platelet aggregation
regulation of blood vessel diameter
cellular oxidant detoxification
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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