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Invitrogen
HBG2 Polyclonal Antibody
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FIGURE: 1 / 2
HBG2 Antibody (PA5-29006) in WB
Western blot analysis of HBG2 in various whole cell extracts (30 µg). Samples were incubated with HBG2 polyclonal antibody (Product # PA5-29006) using a dilution of 1:500 followed by HRP-conjugated anti-rabbit IgG. Separated by 15% SDS-PAGE. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.
Product Details
PA5-29006
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Full length human Hemoglobin gamma G Recombinant protein.
Conjugate
Form
Liquid
Concentration
0.71 mg/mL
Amount
71 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: U87-MG.
Predicted reactivity: Rhesus Monkey (97%), Chimpanzee (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: abnormal hemoglobin; component of the fetal hemoglobin; fetal globin; fetal hemoglobin F subunit gamma 2; G-gamma globin Paulinia; gamma globin; Gamma-2-globin; gamma-globin chain; Hb F Ggamma; Hemoglobin gamma-2 chain; Hemoglobin gamma-G chain; Hemoglobin subunit gamma-2; hemoglobin, gamma G; methemoglobin; unnamed protein product
Gene Aliases: HBG-T1; HBG2; TNCY
UniProt ID: (Human) P69892
Entrez Gene ID: (Human) 3048
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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