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Bethyl Laboratories

HBO Polyclonal Antibody

View all (19) MYST2 antibodies

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HBO Polyclonal Antibody

Product Details

IHC-00632

Applications
Tested Dilution
Publications

Immunohistochemistry (IHC)

1:100-1:500
-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:500
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Region between residue 125 and 175 of human histone acetyltransferase binding to ORC1 (MYST histone acetyltransferase 2).
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Amount

25 µg

Purification

Antigen affinity chromatography

Storage buffer

TBS, pH 7.0 to 8.0, with 0.1% BSA

Contains

0.09% sodium azide

Storage conditions

4°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, X. laevis, X. tropicalis, Chicken, Turkey, Bovine, Dog, Horse, Rabbit, Guinea pig_10141, Pig, Panda and Orangutan

Target Information

This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. This gene was thought initially to be located on chromosome X, however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: EC 2.3.1.48; HBO1; Histone acetyltransferase binding to ORC1; Histone acetyltransferase KAT7; histone acetyltransferase MYST2; K(lysine) acetyltransferase 7; Lysine acetyltransferase 7; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; MYST family member; MYST histone acetyltransferase 2; MYST-2; unnamed protein product

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Gene Aliases: HBO1; HBOA; KAT7; MYST2; ZC2HC7

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UniProt ID: (Human) O95251

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Entrez Gene ID: (Human) 11143

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Function(s)
chromatin binding DNA replication origin binding transcription cofactor activity histone acetyltransferase activity protein binding zinc ion binding H3 histone acetyltransferase activity H4 histone acetyltransferase activity transferase activity transferase activity, transferring acyl groups histone acetyltransferase activity (H3-K14 specific) histone acetyltransferase activity (H3-K23 specific) histone acetyltransferase activity (H4-K5 specific) histone acetyltransferase activity (H4-K8 specific) histone acetyltransferase activity (H4-K12 specific) histone acetyltransferase activity (H3-K4 specific) metal ion binding histone acetyltransferase activity (H4-K16 specific)
Process(es)
regulation of cell growth natural killer cell differentiation DNA replication regulation of DNA replication DNA repair chromatin organization regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter cellular response to DNA damage stimulus internal peptidyl-lysine acetylation regulation of DNA-dependent DNA replication initiation T cell differentiation stress-activated protein kinase signaling cascade positive regulation of DNA-templated transcription, elongation positive regulation of erythrocyte differentiation positive regulation of DNA replication positive regulation of gene expression, epigenetic positive regulation of nucleobase-containing compound metabolic process positive regulation of transcription from RNA polymerase II promoter regulation of cell cycle response to sorbitol response to hydroxyurea response to actinomycin D response to dithiothreitol response to anisomycin DNA replication-dependent chromatin disassembly positive regulation of protein localization to nucleus positive regulation of hematopoietic stem cell proliferation regulation of DNA biosynthetic process regulation of nucleotide-excision repair
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