Proteintech

HBXIP Polyclonal Antibody

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HBXIP Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human hepatocirrhosis using 14492-1-AP (HBXIP antibody) at dilution of 1:50 (under 40x lens).

HBXIP Antibody in Western Blot (WB) — Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 14492-1-AP ( HBXIP Antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

HBXIP Antibody in Flow Cytometry (Flow) — 1X10^6 MCF-7 cells were stained with 0.2ug HBXIP antibody (14492-1-AP, red) and control antibody (blue). Fixed with 4% PFA blocked with 3% BSA (30 min). Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L) with dilution 1:1500.

Product Details

14492-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 9 publications 9 publications

Immunohistochemistry (IHC)

View 8 publications 8 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

Immunoprecipitation (IP)

Assay-dependent

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

HBXIP Fusion Protein Ag5894 (1-173 aa encoded by BC062619)

Conjugate

Unconjugated

Form

Liquid

Concentration

0.22 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Product Specific Information

Immunogen sequence: MEPGAGHLD GHRAGSPSLR QALCDGSAVM FSSKERGRCT VINFVPLEAP LRSTPRSRQV TEACGGEGRA VPLGSEPEWS VGGMEATLEQ HLEDTMKNPS IVGVLCTDSQ GLNLGCRGTL SDEHAGVISV LAQQAAKLTS DPTDIPVVCL ESDNGNIMIQ KHDGITVAVH KMAS (1-173 aa encoded by BC062619)

Target Information

HBXIP, also named as XIP, belongs to the HBXIP family. It is originally identified by its interaction with the C-terminus of hepatitis B virus (HBV) X protein (HBx). HBXIP is a regulator of centrosome dynamics and cytokinesis. HBXIP is able to up-regulate S100A4 though activating STAT4 and inducing DNA methylation of PTEN. HBXIP is a cellular 18kd protein and cytoplasm stain.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

KAT7-mediated CANX (calnexin) crotonylation regulates leucine-stimulated MTORC1 activity.

Autophagy

Yan G,Li X,Zheng Z,Gao W,Chen C,Wang X,Cheng Z,Yu J,Zou G,Farooq MZ,Zhu X,Zhu W,Zhong Q,Yan X

Thu Dec 01 00:00:00 EST 2022

Germacrone Regulates HBXIP-Mediated Cell Cycle, Apoptosis and Promotes the Formation of Autophagosomes to Inhibit the Proliferation of Gastric Cancer Cells.

Frontiers in oncology

Fang X,Tan T,Gao B,Zhao Y,Liu T,Xia Q

Sat Nov 28 00:00:00 EST 2020

Elevated HBXIP expression is associated with aggressive phenotype and poor prognosis in esophageal squamous cell carcinoma.

American journal of cancer research

Xia H,Ma L,Li J,Bai H,Wang D

Thu Oct 01 00:00:00 EDT 2020

Elevated HBXIP expression is associated with aggressive phenotype and poor prognosis in esophageal squamous cell carcinoma.

American journal of cancer research

Xia H,Ma L,Li J,Bai H,Wang D

Thu Oct 01 00:00:00 EDT 2020

Elevated HBXIP expression is associated with aggressive phenotype and poor prognosis in esophageal squamous cell carcinoma.

American journal of cancer research

Xia H,Ma L,Li J,Bai H,Wang D

Thu Oct 01 00:00:00 EDT 2020

Elevated HBXIP expression is associated with aggressive phenotype and poor prognosis in esophageal squamous cell carcinoma.

American journal of cancer research

Xia H,Ma L,Li J,Bai H,Wang D

Thu Oct 01 00:00:00 EDT 2020

HBXIP: a potential prognosis biomarker of colorectal cancer which promotes invasion and migration via epithelial-mesenchymal transition.

Life sciences

Wang X,Feng Q,Yu H,Zhou X,Shan C,Zhang Q,Liu S

Sun Mar 15 00:00:00 EDT 2020

HBXIP: a potential prognosis biomarker of colorectal cancer which promotes invasion and migration via epithelial-mesenchymal transition.

Life sciences

Wang X,Feng Q,Yu H,Zhou X,Shan C,Zhang Q,Liu S

Sun Mar 15 00:00:00 EDT 2020

Trilobatin, a Novel SGLT1/2 Inhibitor, Selectively Induces the Proliferation of Human Hepatoblastoma Cells.

Molecules (Basel, Switzerland)

Wang L,Liu M,Yin F,Wang Y,Li X,Wu Y,Ye C,Liu J

Wed Sep 18 00:00:00 EDT 2019

HBXIP protein overexpression predicts the poor prognosis of pancreatic ductal adenocarcinomas.

Pathology, research and practice

Zhou X,Wang X,Duan J,Sun W,Chen Z,Li Q,Ou Z,Jiang G,Ren X,Liu S

Fri Feb 01 00:00:00 EST 2019

HBXIP protein overexpression predicts the poor prognosis of pancreatic ductal adenocarcinomas.

Pathology, research and practice

Zhou X,Wang X,Duan J,Sun W,Chen Z,Li Q,Ou Z,Jiang G,Ren X,Liu S

Fri Feb 01 00:00:00 EST 2019

HBXIP suppression reduces cell proliferation and migration and its overexpression predicts poor prognosis in non-small-cell lung cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Wang Y,Li N,Che S,Jin T,Piao J,Liu S,Lin Z

Sat Jul 01 00:00:00 EDT 2017

HBXIP suppression reduces cell proliferation and migration and its overexpression predicts poor prognosis in non-small-cell lung cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Wang Y,Li N,Che S,Jin T,Piao J,Liu S,Lin Z

Sat Jul 01 00:00:00 EDT 2017

HBXIP suppression reduces cell proliferation and migration and its overexpression predicts poor prognosis in non-small-cell lung cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Wang Y,Li N,Che S,Jin T,Piao J,Liu S,Lin Z

Sat Jul 01 00:00:00 EDT 2017

HBXIP suppression reduces cell proliferation and migration and its overexpression predicts poor prognosis in non-small-cell lung cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Wang Y,Li N,Che S,Jin T,Piao J,Liu S,Lin Z

Sat Jul 01 00:00:00 EDT 2017

HBXIP suppression reduces cell proliferation and migration and its overexpression predicts poor prognosis in non-small-cell lung cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Wang Y,Li N,Che S,Jin T,Piao J,Liu S,Lin Z

Sat Jul 01 00:00:00 EDT 2017

HBXIP overexpression is correlated with the clinical features and survival outcome of ovarian cancer.

Journal of ovarian research

Wang Y,Sun J,Li N,Che S,Jin T,Liu S,Lin Z

Fri Apr 07 00:00:00 EDT 2017

HBXIP overexpression is correlated with the clinical features and survival outcome of ovarian cancer.

Journal of ovarian research

Wang Y,Sun J,Li N,Che S,Jin T,Liu S,Lin Z

Fri Apr 07 00:00:00 EDT 2017

HBXIP overexpression is correlated with the clinical features and survival outcome of ovarian cancer.

Journal of ovarian research

Wang Y,Sun J,Li N,Che S,Jin T,Liu S,Lin Z

Fri Apr 07 00:00:00 EDT 2017

The oncoprotein hepatitis B X-interacting protein promotes the migration of ovarian cancer cells through the upregulation of S-phase kinase-associated protein 2 by Sp1.

International journal of oncology

Xu F,Zhu X,Han T,You X,Liu F,Ye L,Zhang X,Wang X,Yao Y

Tue Jul 01 00:00:00 EDT 2014

The oncoprotein hepatitis B X-interacting protein promotes the migration of ovarian cancer cells through the upregulation of S-phase kinase-associated protein 2 by Sp1.

International journal of oncology

Xu F,Zhu X,Han T,You X,Liu F,Ye L,Zhang X,Wang X,Yao Y

Tue Jul 01 00:00:00 EDT 2014

The oncoprotein HBXIP up-regulates Skp2 via activating transcription factor E2F1 to promote proliferation of breast cancer cells.

Cancer letters

Xu F,You X,Liu F,Shen X,Yao Y,Ye L,Zhang X

Sat Jun 01 00:00:00 EDT 2013

The oncoprotein HBXIP up-regulates Skp2 via activating transcription factor E2F1 to promote proliferation of breast cancer cells.

Cancer letters

Xu F,You X,Liu F,Shen X,Yao Y,Ye L,Zhang X

Sat Jun 01 00:00:00 EDT 2013

The oncoprotein HBXIP up-regulates Skp2 via activating transcription factor E2F1 to promote proliferation of breast cancer cells.

Cancer letters

Xu F,You X,Liu F,Shen X,Yao Y,Ye L,Zhang X

Sat Jun 01 00:00:00 EDT 2013

The oncoprotein HBXIP up-regulates Skp2 via activating transcription factor E2F1 to promote proliferation of breast cancer cells.

Cancer letters

Xu F,You X,Liu F,Shen X,Yao Y,Ye L,Zhang X

Sat Jun 01 00:00:00 EDT 2013

The oncoprotein HBXIP uses two pathways to up-regulate S100A4 in promotion of growth and migration of breast cancer cells.

The Journal of biological chemistry