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          • Primary Antibodies ›
          • HCLS1 Antibodies

          Abnova

          HCLS1 Polyclonal Antibody, MaxPab™

          View all (27) HCLS1 antibodies

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          Cite HCLS1 Polyclonal Antibody, MaxPab™

          Additional Information:
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          • Antibody Testing Data (1)
          HCLS1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          HCLS1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          HCLS1 Antibody (H00003059-B01P) in WB

          Western Blot analysis of HCLS1 expression in transfected 293T cell line by HCLS1 MaxPab polyclonal antibody. Lane 1: HCLS1 transfected lysate(53.46 KDa). Lane 2: Non-transfected lysate. . {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          HCLS1 Antibody in Western Blot (WB)

          Product Details

          H00003059-B01P

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Mouse / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          HCLS1 (NP_005326.1, 1 a.a. approximately 486 a.a) full-length human protein.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5-1 mg/mL

          Amount

          50 µg

          Purification

          Protein A

          Storage buffer

          PBS, pH 7.4

          Contains

          no preservative

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Product may be used with Western Blot (Transfected lysate).

          The Isotype of this product is composed of an IgG Mixture.

          Immunogen sequence: MWKSVVGHDV SVSVETQGDD WDTDPDFVND ISEKEQRWGA KTIEGSGRTE HINIHQLRNK VSEEHDVLRK KEMESGPKAS HGYGGRFGVE RDRMDKSAVG HEYVAEVEKH SSQTDAAKGF GGKYGVERDR ADKSAVGFDY KGEVEKHTSQ KDYSRGFGGR YGVEKDKWDK AALGYDYKGE TEKHESQRDY AKGFGGQYGI QKDRVDKSAV GFNEMEAPTT AYKKTTPIEA ASSGARGLKA KFESMAEEKR KREEEEKAQQ VARRQQERKA VTKRSPEAPQ PVIAMEEPAV PAPLPKKISS EAWPPVGTPP SSESEPVRTS REHPVPLLPI RQTLPEDNEE PPALPPRTLE GLQVEEEPVY EAEPEPEPEP EPEPENDYED VEEMDRHEQE DEPEGDYEEV LEPEDSSFSS ALAGSSGCPA GAGAGAVALG ISAVALYDYQ GEGSDELSFD PDDVITDIEM VDEGWWRGRC HGHFGLFPAN YVKLLE

          Target Information

          Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression. [UniProt]

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: HCLS1; Hematopoietic cell-specific LYN substrate 1; Hematopoietic lineage cell-specific protein; LckBP1; p75; unnamed protein product

          View more View less

          Gene Aliases: CTTNL; HCLS1; HS1; lckBP1; p75

          View more View less

          UniProt ID: (Human) P14317

          View more View less

          Entrez Gene ID: (Human) 3059

          View more View less

          Function(s)
          protein binding SH3 domain binding protein kinase binding signaling adaptor activity macromolecular complex binding actin filament binding RNA polymerase II sequence-specific DNA binding transcription factor binding
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter regulation of transcription, DNA-templated actin filament organization signal transduction positive regulation of cell proliferation response to hormone erythrocyte differentiation regulation of actin filament polymerization positive regulation of granulocyte differentiation intracellular signal transduction granulocyte colony-stimulating factor signaling pathway positive regulation of protein import into nucleus positive regulation of macrophage differentiation positive regulation of transcription from RNA polymerase II promoter nuclear transport positive regulation of protein kinase B signaling cellular response to cytokine stimulus negative regulation of leukocyte apoptotic process
          It has to be done as per old AB suggested Products section.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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