Keep as concentrated solution.
Positive Control: 293T, A431, HeLa, HepG2, U87-MG, SK-N-SH, NIH3T3, Rat-2, E8.5 embryo.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Histone deacetylase (HDAC) is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones-H2A, H2B, H3, and H4. Histone deacetylation gives a tag for epigenetic repression and plays and important role in transcriptional regulation, cell cycle progression, and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp686H12203 antibody; GON-10 antibody; HD1; HD1 antibody; HDAC1 antibody; Histone deacetylase 1; histone deacetylase 1 antibody; reduced potassium dependency; reduced potassium dependency, yeast homolog-like 1; RPD3 antibody; RPD3L1 antibody; yeast homolog-like 1 antibody
Gene Aliases: GON-10; HD1; HDAC1; Hdac1-ps; MommeD5; RPD3; RPD3L1