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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Rabbit Polyclonal to HDAC 10|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay dependent|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-23496 detects HDAC 10 in Human samples.
PA1-23496 has been successfully used in ELISA and Western Blot procedures.
PA1-23496 immunogen corresponds to Rabbit Polyclonal to HDAC 10.
A novel class II histone deacetylase, HDAC10 is most similar to HDAC6. Both contain a unique, putative second catalytic domain not found in other HDACs. In HDAC10, however, this domain is not functional. Unlike HDAC6, which is normally a cytoplasmic deacetylase, HDAC10 resides in both the nucleus and cytoplasm. Data suggests that HDAC10 may play roles both in the nucleus, as a transcriptional modulator, and in the cytoplasm in an unidentified role. HDAC10 variants seem present in certain cell lines and tissues that are as of yet not characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
DKFZp761B039; MGC149722; RP3-402G11.7