This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated. View Details
The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HD2; HDAC2; Histone deacetylase 2; RPD3; transcriptional regulator homolog RPD3; YAF1; YY1 transcription factor-binding protein; YY1-associated factor 1
Gene Aliases: D10Wsu179e; HD2; HDAC2; mRPD3; RPD3; YAF1; Yy1bp