Applications | Tested Dilution | Publications |
---|---|---|
Immunocytochemistry (ICC/IF) |
1-10 µg/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Dog, Hamster, Human, Mouse, Non-human primate, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic peptide corresponding to residues C T(475) D T K G T K S E Q L S N P(488) of human HDAC2 |
Conjugate |
Alexa Fluor™ 555 |
Excitation/Emission Profile |
View spectra |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.4, with 1mg/mL BSA |
Contains |
0.05% sodium azide |
Storage conditions |
4° C, store in dark, DO NOT FREEZE! |
RRID |
AB_2664285 |
PA1861A555 detects histone deacetylase 2 (HDAC2) from canine, hamster, human, mouse, non-human primate, rat tissues and cells.
The PA1861A555 immunogen is a synthetic peptide corresponding to residues C T(475) D T K G T K S E Q L S N P(488) of human HDAC2. This immunizing peptide (Cat. # PEP-070) is available for use in neutralization and control experiments.
HDAC2 belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HD2; hdac 2; hdac-2; Histone deacetylase 2; histone deacetylase 2-like protein; transcriptional regulator homolog RPD3; YY1 transcription factor-binding protein; YY1-associated factor 1
Gene Aliases: D10Wsu179e; HD2; HDAC2; I79_010219; mRPD3; RPD3; YAF1; Yy1bp
UniProt ID: (Human) Q92769, (Mouse) P70288
Entrez Gene ID: (Human) 3066, (Dog) 475035, (Mouse) 15182, (Rat) 84577, (Chinese hamster) 100764557
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support