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      HDAC3 Polyclonal Antibody

      See 9 other HDAC3 antibodies ›
      HDAC3 Polyclonal Antibody for Western Blot, IF, ICC, IHC (P), IP and ChIP

      Catalog#: PA5-29026 Invitrogen

      Catalog # Size Price (USD) Qty Datasheet
      PA5-29026 100 µL
      349.00
      Please enter a quantity in the range of 1 to 199.
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      Product Details

      Bioinformatics

      Documents
      Details
      Tested species reactivity Human
      Host / Isotype Rabbit / IgG
      Class Polyclonal
      Type Antibody
      Immunogen Synthetic peptide corresponding to a region within amino acids 361 and 428 of Human HDAC3
      Conjugate Unconjugated
      Form Liquid
      Concentration 1 mg/ml
      Purification Antigen affinity chromatography
      Storage buffer 0.1M tris glycine, pH 7, with 10% glycerol
      Contains 0.01% thimerosal
      Storage Conditions -20° C, Avoid Freeze/Thaw Cycles
      Tested Applications Dilution *
      ChIP assay (ChIP) Assay-dependent
      Immunocytochemistry (ICC) 1:100-1:1000
      Immunofluorescence (IF) 1:100-1:1000
      Immunohistochemistry (Paraffin) (IHC (P)) 1:100-1:1000
      Immunoprecipitation (IP) 1:1000
      Western Blot (WB) 1:500-1:3000

      * Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

      Product Specific Information

      PA5-29026 targets HDAC3 in IF, IHC (P), and WB applications and shows reactivity with Human samples.

      The PA5-29026 immunogen is synthetic peptide corresponding to a region within amino acids 361 and 428 of Human HDAC3.

      Background/Target Information

      Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

      For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

      Documents

      Material safety data sheets (MSDS)

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