PA5-29937 targets HDAC7 in IF, IP, IHC (P), ChIP and WB applications and shows reactivity with Human samples.
The PA5-29937 immunogen is recombinant fragment corresponding to a region within amino acids 737 and 952 of Human HDAC7.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HD7; HD7A; HDAC7A; Histone deacetylase 7; Histone deacetylase 7A
Gene Aliases: HD7; HD7A; HDAC7; HDAC7A
UniProt ID: (Human) Q8WUI4
Entrez Gene ID: (Human) 51564