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Abnova
HDAC7A Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 1
HDAC7A Antibody (H00051564-D01P) in WB
Western Blot analysis of HDAC7 expression in transfected 293T cell line (H00051564-T02) by HDAC7 MaxPab polyclonal antibody.
Lane 1: HDAC7A transfected lysate(29.60 KDa).
Lane 2: Non-transfected lysate.
Lane 1: HDAC7A transfected lysate(29.60 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00051564-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
HDAC7A (AAH06453.1, 1 a.a. approximately 276 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MGFCFFNSVA IACRQLQQQS KASKILIVDW DVHHGNGTQQ TFYQDPSVLY ISLHRHDDGN FFPGSGAVDE VGAGSGEGFN VNVAWAGGLD PPMGDPEYLA AFRIVVMPIA REFSPDLVLV SAGFDAAEGH PAPLGGYHVS AKCFGYMTQQ LMNLAGGAVV LALEGGHDLT AICDASEACV AALLGNRVDP LSEEGWKQKP NLNAIRSLEA VIRVHSKYWG CMQRLASCPD SWVPRVPGAD KEEVEAVTAL ASLSVGILAE DRPSEQLVEE EEPMNL
Target Information
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HD7; HD7a; hdac-7; Histone deacetylase 7; Histone deacetylase 7A; Protein deacetylase HDAC7; unnamed protein product
Gene Aliases: HD7; HD7A; HDAC7; HDAC7A
UniProt ID: (Human) Q8WUI4
Entrez Gene ID: (Human) 51564
chromatin binding
transcription corepressor activity
histone deacetylase activity
protein kinase C binding
protein binding
hydrolase activity
SUMO transferase activity
protein kinase binding
protein deacetylase activity
metal ion binding
14-3-3 protein binding
DNA-binding transcription factor binding
histone deacetylase activity, hydrolytic mechanism
negative regulation of transcription from RNA polymerase II promoter
vasculogenesis
chromatin organization
protein deacetylation
cell-cell junction assembly
negative regulation of macromolecule biosynthetic process
protein sumoylation
negative regulation of interleukin-2 production
regulation of gene expression, epigenetic
negative regulation of osteoblast differentiation
negative regulation of transcription, DNA-templated
regulation of mRNA processing
positive regulation of cell migration involved in sprouting angiogenesis
membraneless organelle assembly
negative regulation of NIK/NF-kappaB signaling
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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