|Western Blot (WB)||1:1000-1:10,000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 139 and 377 of Human HDAC8|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29885 targets HDAC8 in WB applications and shows reactivity with Human, Rat and mouse samples.
The PA5-29885 immunogen is recombinant fragment corresponding to a region within amino acids 139 and 377 of Human HDAC8.
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HD8; HDACL1; Histone deacetylase 8; histone deacetylase-like 1; RPD3
Gene Aliases: 2610007D20Rik; CDA07; CDLS5; HD8; HDAC8; HDACL1; MRXS6; RGD1562895; RPD3; WTS
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