Recommended positive controls: Jurkat, Raji, K562, NCI-H929.
Predicted reactivity: Mouse (92%), Rat (91%), Chicken (81%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The biogenic amine histamine is an important modulator of numerous physiologic processes, including neurotransmission, gastric acid secretion, and smooth muscle tone. The biosynthesis of histamine from histidine is catalyzed by the enzyme L-histidine decarboxylase (HDC; EC 188.8.131.52). This homodimeric enzyme is a pyridoxal phosphate (PLP)-dependent decarboxylase and is highly specific for its histidine substrate.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HDC; Histidine decarboxylase; MGC163399
Gene Aliases: HDC
UniProt ID: (Human) P19113
Entrez Gene ID: (Human) 3067