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Product Details
PA5-92411
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human HDGF (NP_0044851)
Conjugate
Form
Liquid
Concentration
0.32 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2806482
Product Specific Information
Immunogen sequence: MSRSNRQKEY KCGDLVFAKM KGYPHWPARI DEMPEAAVKS TANKYQVFFF GTHETAFLGP KDLFPYEESK EKFGKPNKRK GFSEGLWEIE NNPTVKASGY QSSQKKSCVE EPEPEPEAAE GDGDKKGNAE GSSDEEGKLV IDEPAKEKNE KGALKRRAGD LLEDSPKRPK EAENPEGEEK EAATLEVERP LPMEVEKNST PSEPGSGRGP PQEEEEEEDE EEEATKEDAE APGIRDHESL; Positive Samples: 22Rv1, HeLa, A-549, 293T, U-251MG, MCF7, BT-474; Cellular Location: Cytoplasm, Nucleus
Target Information
HDGF is a member of the hepatoma-derived growth factor family. This protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp686J1764; FLJ96580; HDGF; Hepatoma-derived growth factor; High mobility group protein 1-like 2; HMG-1L2
Gene Aliases: AI118077; D3Ertd299e; HDGF; HMG1L2; Tdrm1
UniProt ID: (Human) P51858, (Rat) Q8VHK7, (Mouse) Q8BPG7
Entrez Gene ID: (Human) 3068, (Rat) 114499, (Mouse) 15191
nucleotide binding
RNA polymerase II transcription corepressor activity
transcription corepressor binding
DNA binding
growth factor activity
heparin binding
poly(A) RNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein binding
transcription cofactor
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
signal transduction
cell proliferation
IRE1-mediated unfolded protein response
cellular process
protein localization to nucleus
positive regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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