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HEG1 Polyclonal Antibody
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FIGURE: 1 / 4
HEG1 Antibody (BS-15449R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded mouse brain tissue; Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (normal goat serum) at 37°C for 20min; Antibody incubation with Rabbit Anti-HEG1 Polyclonal Antibody, Unconjugated (bs-15449R) at 1:400 overnight at 4°C, followed by a biotin conjugated secondar... View More
Product Details
BS-15449R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human HEG1, amino acids 1151-1381.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Receptor component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity May act through the stabilization of endothelial cell junctions. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: heart development protein with EGF-like domains 1; heart of glass; HEG homolog 1; Protein HEG homolog 1; unnamed protein product
Gene Aliases: 4632417D23Rik; 5530401I02Rik; 9530025L16Rik; BC038614; Gm629; HEG; HEG1; KIAA1237; MST112; MSTP112; OTTMUSG00000027315; RGD1564641
UniProt ID: (Human) Q9ULI3
Entrez Gene ID: (Human) 57493, (Rat) 689710, (Mouse) 77446
vasculogenesis
in utero embryonic development
endothelial cell development
endothelial cell morphogenesis
vasculature development
lymph vessel development
lymph circulation
cardiac atrium morphogenesis
ventricular trabecula myocardium morphogenesis
ventricular septum development
heart development
post-embryonic development
lung development
negative regulation of Rho protein signal transduction
multicellular organism growth
cell-cell junction organization
venous blood vessel morphogenesis
regulation of body fluid levels
cardiac muscle tissue growth
pericardium development
regulation of macromolecule metabolic process
regulation of biological quality
positive regulation of fibroblast growth factor production
protein localization to cell junction
negative regulation of membrane permeability
negative regulation of Rho-dependent protein serine/threonine kinase activity
cell-cell junction assembly
multicellular organism development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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