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Product Details
11955-1-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:1,000-1:5,000 | View 1 publication 1 publication |
Immunocytochemistry (ICC/IF) |
1:10-1:100 | View 1 publication 1 publication |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
Miscellaneous PubMed (Misc) |
- | View 1 publication 1 publication |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
HELLS Fusion Protein Ag2558 (1-348 aa encoded by BC031004) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.3 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
Immunogen sequence: MFGSSEKET IELSPTGRPK RRTRKSINYS KIDDFPNELE KLISQIQPEV DRERAVVEVN IPVESEVNLK LQNIMMLLRK CCNHPYLIEY PIDPVTQEFK IDEELVTNSG KFLILDRMLP ELKKRGHKVL LFSQMTSMLD ILMDYCHLRD FNFSRLDGSM SYSEREKNMH SFNTDPEVFI FLVSTRAGGL GINLTAADTV IIYDSDWNPQ SDLQAQDRCH RIGQTKPVVV YRLVTANTID QKIVERAAAK RKLEKLIIHK NHFKGGQSGL NLSKNFLDPK ELMELLKSRD YEREIKGSRE KVISDKDLEL LLDRSDLIDQ MNASGPIKEK MGIFKILENS EDSSPECLF (1-348 aa encoded by BC031004 )
Target Information
This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: helicase, lymphoid specific; hells; Lymphocyte-specific helicase; Lymphoid-specific helicase; Proliferation-associated SNF2-like protein; SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6; SWI/SNF2-related, matrix-associated, actin-dependent regulator of chromatin, subfamily A, member 6; TBC1D12: TBC1 domain family, member 12
Gene Aliases: AI323785; E130115I21Rik; HELLS; ICF4; LSH; Lysh; Nbla10143; PASG; SMARCA6; Tbc1d12; YFK8
UniProt ID: (Human) Q9NRZ9, (Mouse) Q60848
Entrez Gene ID: (Human) 3070, (Mouse) 15201, (Rat) 294071
urogenital system development
DNA methylation
chromatin silencing
methylation-dependent chromatin silencing
transcription, DNA-templated
regulation of transcription, DNA-templated
cell cycle
mitotic nuclear division
multicellular organism development
maintenance of DNA methylation
lymphocyte differentiation
pericentric heterochromatin assembly
negative regulation of apoptotic process
cell division
negative regulation of intrinsic apoptotic signaling pathway
lymphocyte proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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