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Product Details
24730-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
HELT Fusion Protein Ag20618 (54-241 aa encoded by BC140795)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: ILEMTVQYL RALHSADFPR GREKELLAEF ANYFHYGYHE CMKNLVHYLT TVERMETKDT KYARILAFLQ SKARLGAEPA FPPLGSLPEP DFSYQLHPAG PEFAGHSPGE AAVFPQGSGA GPFPWPPGAA RSPALPYLPS APVPLASPAQ QHSPFLTPVQ GLDRHYLNLI GHAHPNALNL HTPQHPPVL (54-241 aa encoded by BC140795)
Target Information
Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGCG-3'.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bHLH transcription factor megane; Hairy and enhancer of split-related protein HELT; helt bHLH transcription factor; HES/HEY-like transcription factor; HES/HEY-like transcription factor, pseudogene 1; Heslike; Hey-like transcription factor; Hey-like transcriptional repressor; Megane bHLH factor; mesencephalic GABAergic neurons enhancer of split related protein; Protein Hes-like; Protein megane
Gene Aliases: A830086M02; bHLHb44; HCM1228; HELT; Helt-ps1; HESL; megane; Mgn; RGD1564073
UniProt ID: (Human) A6NFD8, (Mouse) Q7TS99
Entrez Gene ID: (Human) 391723, (Mouse) 234219, (Rat) 498633
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein homodimerization activity
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein dimerization activity
basic helix-loop-helix transcription factor
negative regulation of transcription from RNA polymerase II promoter
suckling behavior
transcription, DNA-templated
central nervous system development
post-embryonic development
multicellular organism aging
GABAergic neuron differentiation in basal ganglia
multicellular organism growth
positive regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
nervous system development
gene expression
cell differentiation
neuron differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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