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Invitrogen
HELZ2 Polyclonal Antibody
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Product Details
PA5-101743
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human HELZ2(Accession Q9BYK8), corresponding to amino acid residues V2244-Y2294.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total PRIC285.
Target Information
The protein encoded by this gene is a nuclear transcriptional co-activator for peroxisome proliferator activated receptor alpha. The encoded protein contains a zinc finger and is a helicase that appears to be part of the peroxisome proliferator activated receptor alpha interacting complex. This gene is a member of the DNA2/NAM7 helicase gene family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 3'-5' exoribonuclease HELZ2; ATP-dependent helicase PRIC285; ATP-dependent RNA helicase PRIC285; Helicase with zinc finger 2, transcriptional coactivator; Helicase with zinc finger domain 2; PDIP1; PDIP1-alpha; peroxisomal proliferator-activated receptor A interacting complex 285; Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein; peroxisomal proliferator-activated receptor alpha-interacting cofactor complex, 285 kD subunit; PPAR gamma DBD-interacting protein 1; PPAR gamma-DNA-binding domain interacting protein1; PPAR-alpha-interacting complex protein 285; PPAR-gamma DBD-interacting protein 1; PPAR-gamma DNA-binding domain-interacting protein 1; PPARG-DBD-interacting protein 1; PPARgamma-DNA-binding domain-interacting protein1; PRIC complex; PRIC285; UvrD/REP helicase; unnamed protein product
Gene Aliases: HELZ2; KIAA1769; mKIAA1769; mPDIP1; PDIP-1; PDIP1; PRIC285
UniProt ID: (Human) Q9BYK8, (Mouse) E9QAM5
Entrez Gene ID: (Human) 85441, (Mouse) 229003
nucleotide binding
3'-5'-exoribonuclease activity
DNA binding
transcription coactivator activity
RNA binding
RNA helicase activity
helicase activity
nuclease activity
exonuclease activity
ribonuclease activity
protein binding
ATP binding
zinc ion binding
exoribonuclease II activity
hydrolase activity
ATPase activity
metal ion binding
ligand-dependent nuclear receptor transcription coactivator activity
poly(A) RNA binding
DNA metabolism protein
nucleic acid metabolism protein
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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