This gen encodes a member of the HERC protein family. This protein stimulates guanine nucleotide exchange on ARF1 and Rab proteins. This protein may be involved in membrane transport processes.
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Protein Aliases: guanine nucleotide exchange factor p532; hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1; HECT domain and RCC1-like domain-containing protein 1; HECT-type E3 ubiquitin transferase HERC1; p532; p619; Probable E3 ubiquitin-protein ligase HERC1
Gene Aliases: HERC1; p532; p619
UniProt ID: (Human) Q15751
Entrez Gene ID: (Human) 8925
Molecular Function: guanyl-nucleotide exchange factor